An Overview of NMR in Medicine

An Overview of NMR in Medicine PDF Author: D. I. Hoult
Publisher:
ISBN:
Category : Magnetic resonance imaging
Languages : en
Pages : 24

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Book Description

An Overview of NMR in Medicine

An Overview of NMR in Medicine PDF Author: D. I. Hoult
Publisher:
ISBN:
Category : Magnetic resonance imaging
Languages : en
Pages : 24

Get Book Here

Book Description


NMR-Tomography and -Spectroscopy in Medicine

NMR-Tomography and -Spectroscopy in Medicine PDF Author: Klaus Roth
Publisher: Springer Science & Business Media
ISBN: 3642697410
Category : Medical
Languages : en
Pages : 139

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Book Description
Even the earliest applications of nuclear magnetic resonance (NMR) spectroscopy and tomography to medical inquiries, using experimental apparatus that was primitive by today's standards, demonstrated the extraordinary potential of the NMR method. The subsequent rapid advances in this area were due largely to the ef forts of commercial manufacturers, who, by improving magnet and computer designs, were able to produce and market instruments having a remarkable image quality. Experimental data from the ftrst systematic studies on the medical uses of NMR leave little doubt that NMR will gain a permanent place in clinical diagnosis. The clinician, then, is confronted with an entirely new diagnostic modality. Because NMR has been used extensively in chemistry and physics for years, a great many textbooks are already available on the subject. However, the majority of these have been written for the natural scientist who is well versed in mathematics and physics. Assumptions are made and terms are used that would not be appro priate for a medical or biochemical text. The goal of this introduc tion, therefore, is to discuss the principles of the NMR technique in terms that are meaningful to the medical student and medical pro fessional.

NMR in Medicine and Biology

NMR in Medicine and Biology PDF Author: Karl H. Hausser
Publisher: Springer Science & Business Media
ISBN: 3642761046
Category : Science
Languages : en
Pages : 228

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Book Description
0 e From the reviews of the German edition: "NMR: readable yet professional... Through this book the reader with a scientific background becomes familiar with all important NMR phenomena, methods and conceptions... The great amount of carefully drawn figures and skillfully selected biologically relevant spectra and figures are an decisive bridge to the ... aim, to convey the NMR basics without mathematics. Besides biologists and physicians the book can be highly recommended to physicists and chemists..." #Nachrichten a. d. Chemie, Technik u. Laboratorien#1 "An extraordinary NMR textbook ... The authors succeeded in presenting the subject vividly. This book is clearly set out and easy to follow at a glance, and its numerous figures are extremely well done." #Labo#2

Nuclear Magnetic Resonance Imaging in Medicine and Biology

Nuclear Magnetic Resonance Imaging in Medicine and Biology PDF Author: P. G. Morris
Publisher: Oxford University Press, USA
ISBN:
Category : Language Arts & Disciplines
Languages : en
Pages : 412

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Book Description
The aim of this book is to give a sound physical understanding of the theory and practice of NMR imaging, a field which has grown rapidly in recent years, to the point that clinical imaging systems have become commercially available worldwide and many techniques have evolved.

Applications of NMR Spectroscopy

Applications of NMR Spectroscopy PDF Author: Atta-ur-Rahman
Publisher: Bentham Science Publishers
ISBN: 168108287X
Category : Science
Languages : en
Pages : 289

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Book Description
Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The fifth volume of the series features several reviews focusing on NMR spectroscopic techniques for identifying natural and synthetic compounds (polymer and peptide characterization, GABA in tinnitus affected mice), medical diagnosis and therapy (gliomas) and food analysis. The spectroscopic methods highlighted in this volume include high resolution proton magnetic resonance spectroscopy and solid state NMR.

NMR in Medicine

NMR in Medicine PDF Author: American Association of Physicists in Medicine. Summer School
Publisher: American Institute of Physics
ISBN:
Category : Medical
Languages : en
Pages : 616

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Book Description
Over the past decade, we have witnessed a dramatic acceleration in the application of magnetic resonance techniques within the medical sciences. Following the original experimental demonstration of the NMR phenomenon by Bloch and Purcell in 1946, emphasis was directed toward the study of physical materials: however, in the 1950's and 1960's, research was reported on the use of NMR to investigate the properties of biological materials including cell systems, excised muscle tissue and certain in vivo models. This book fully discusses this important topic.

Magnetic Resonance in Medicine

Magnetic Resonance in Medicine PDF Author: Peter A. Rinck
Publisher: BoD – Books on Demand
ISBN: 3746095182
Category : Medical
Languages : en
Pages : 434

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Book Description
Originally developed in the laboratory of Nobel Prize winner Paul C. Lauterbur in the early 1980s, the 12th edition (2018) of this standard textbook has been completely revised, updated, and new critical remarks and comments were added. The author, Peter A. Rinck, is one of the pioneers of nuclear magnetic resonance in medicine and of magnetic resonance imaging. Radiology: One of the most lucid and best illustrated introductory MR texts. European Radiology: An outstanding book, an excellent well-proven didactic approach. Journal of Magnetic Resonance imaging (JMRI): The book more than fulfills its attempted purpose. Amazon Review: This text is by far the best treatise of MRI at the basic level. Academic Radiology: In summary, it is not only an ideal first text, but it's a bargain. Fortschr Röntgenstr (RöFo): In fact, an MR expert has finally succeeded in putting himself in the MR beginner's shoes, explaining the necessary basic knowledge in a very vivid and entertaining way. The author: The perfect book for those wanting to do research and needing to check or refresh the basics and recent developments.

NMR Imaging in Biomedicine

NMR Imaging in Biomedicine PDF Author: P Mansfield
Publisher: Elsevier
ISBN: 0323154069
Category : Science
Languages : en
Pages : 365

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Book Description
NMR Imaging in Biomedicine: Advances in Magnetic Resonance discusses significant advances in NMR imaging and its application to the field of biomedicine. This book is organized into 10 chapters that cover the classification, methods, imaging regimes, and the potential use of NMR imaging in medicine. After discussing the basic theoretical ideas of NMR and its application to NMR imaging, this book presents mathematical analyses of the various NMR techniques, focusing primarily on the comparison in terms of imaging speed and data-acquisition rate. It also covers a number of practical ranges or imaging regimes in terms of sensitivity, sample size, and operating frequency. Significant topics on potential application of NMR imaging in medicine, apparatus requirements in the instrumentation of NMR imaging machines, and the principles of biomagnetic effects are discussed in other chapters. The considered biomagnetic effects are categorized into three main groups: the effects of static magnetic fields, the effects of relatively slow varying time-dependent fields, and radio-frequency magnetic fields. This book is of great value to radiologists, medical physicists, neuroradiologists, anatomists, physiologists, and postgraduate students of NMR imaging.

NMR Spectroscopy in Pharmaceutical Analysis

NMR Spectroscopy in Pharmaceutical Analysis PDF Author: Iwona Wawer
Publisher: Elsevier
ISBN: 008095152X
Category : Science
Languages : en
Pages : 525

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Book Description
For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

NMR Spectroscopy in Drug Development and Analysis

NMR Spectroscopy in Drug Development and Analysis PDF Author: Ulrike Holzgrabe
Publisher: John Wiley & Sons
ISBN: 352761365X
Category : Medical
Languages : en
Pages : 312

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Book Description
Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging. In short, this book covers all aspects of drug analysis.