Experimental Design for Biologists PDF Download
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Author: David J. Glass
Publisher: CSHL Press
ISBN: 0879697350
Category : Biology
Languages : en
Pages : 211
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Book Description
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.
Author: David J. Glass
Publisher: CSHL Press
ISBN: 0879697350
Category : Biology
Languages : en
Pages : 211
Get Book Here
Book Description
The effective design of scientific experiments is critical to success, yet graduate students receive very little formal training in how to do it. Based on a well-received course taught by the author, Experimental Design for Biologistsfills this gap. Experimental Design for Biologistsexplains how to establish the framework for an experimental project, how to set up a system, design experiments within that system, and how to determine and use the correct set of controls. Separate chapters are devoted to negative controls, positive controls, and other categories of controls that are perhaps less recognized, such as “assumption controls†and “experimentalist controls†. Furthermore, there are sections on establishing the experimental system, which include performing critical “system controls†. Should all experimental plans be hypothesis-driven? Is a question/answer approach more appropriate? What was the hypothesis behind the Human Genome Project? What color is the sky? How does one get to Carnegie Hall? The answers to these kinds of questions can be found in Experimental Design for Biologists. Written in an engaging manner, the book provides compelling lessons in framing an experimental question, establishing a validated system to answer the question, and deriving verifiable models from experimental data. Experimental Design for Biologistsis an essential source of theory and practical guidance in designing a research plan.
Author: Gerald Peter Quinn
Publisher: Cambridge University Press
ISBN: 9780521009768
Category : Mathematics
Languages : en
Pages : 560
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Book Description
Regression, analysis of variance, correlation, graphical.
Author: David Heath
Publisher: CRC Press
ISBN: 9780203499245
Category : Mathematics
Languages : en
Pages : 390
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Book Description
This illustrated textbook for biologists provides a refreshingly clear and authoritative introduction to the key ideas of sampling, experimental design, and statistical analysis. The author presents statistical concepts through common sense, non-mathematical explanations and diagrams. These are followed by the relevant formulae and illustrated by w
Author: Malcolm Gordon
Publisher: Univ of California Press
ISBN: 0520930630
Category : Nature
Languages : en
Pages : 360
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Book Description
We are living in the early stages of a looming worldwide extinction crisis. Abundant evidence shows that the current rate of species extinctions is nearing its highest level since the asteroid collision 65 million years ago, and that humans are largely responsible. This book addresses the urgent need to understand and find solutions to this crisis. Written by an international team of contributors who are among the best-known and most active experimental biologists working in the field of conservation biology today, it provides a unique approach by focusing on individual species rather than whole plant and animal communities. Emphasizing throughout how conservation biology can benefit from an experimental approach, the book looks at a wide range of terrestrial and aquatic species—from giant pandas and tree snails to sea turtles and Steller sea lions—and demonstrates what can be done both to preserve rare species and to combat invasive organisms. Finally, contributors show how we can bridge the gap between policy makers and research scientists in order to develop lasting solutions to these problems.
Author: Stanley E. Lazic
Publisher: Cambridge University Press
ISBN: 1316810674
Category : Medical
Languages : en
Pages : 429
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Book Description
Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.
Author: Graeme D. Ruxton
Publisher:
ISBN: 9780191975202
Category : Experimental design
Languages : en
Pages : 0
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Book Description
Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
Author: Theodore Garland
Publisher: Univ of California Press
ISBN: 0520261801
Category : Nature
Languages : en
Pages : 752
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Book Description
This volume summarizes studies in experimental evolution, outlining current techniques and applications, and presenting the field's range of research.
Author: John K. Gilbert
Publisher: Springer Science & Business Media
ISBN: 1402052677
Category : Education
Languages : en
Pages : 326
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Book Description
External representations (pictures, diagrams, graphs, concrete models) have always been valuable tools for the science teacher. This book brings together the insights of practicing scientists, science education researchers, computer specialists, and cognitive scientists, to produce a coherent overview. It links presentations about cognitive theory, its implications for science curriculum design, and for learning and teaching in classrooms and laboratories.
Author: Jay L. Nadeau
Publisher: CRC Press
ISBN: 1439897409
Category : Science
Languages : en
Pages : 658
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Book Description
Increasing numbers of physicists, chemists, and mathematicians are moving into biology, reading literature across disciplines, and mastering novel biochemical concepts. To succeed in this transition, researchers must understand on a practical level what is experimentally feasible. The number of experimental techniques in biology is vast and often s
Author: Michael H. Herzog
Publisher: Springer
ISBN: 3030034992
Category : Science
Languages : en
Pages : 146
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Book Description
This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate. Finally, the textbook shows how complex statistics can be avoided by using clever experimental design. Both non-scientists and students in Biology, Biomedicine and Engineering will benefit from the book by learning the statistical basis of scientific claims and by discovering ways to evaluate the quality of scientific reports in academic journals and news outlets.
