An Analysis of the D.c. Component of the Local Electroretinogram in the Intact Eye of the Cat

An Analysis of the D.c. Component of the Local Electroretinogram in the Intact Eye of the Cat PDF Author: Roy Herbert Steinberg
Publisher:
ISBN:
Category : Electroretinography
Languages : en
Pages : 52

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Book Description
The local electroretinogram (LERG) was recorded with microelectrodes from the intact eye in response to focused spots and annuli delivered by a dual-beam ophthalmoscope. The d.c. component was readily isolated from the b-wave on the basis of a lower threshold, smaller summation area, and greater resistance to light adaptation, thereby supporting a hypothesis that separates these components. At high flash intensities the d.c. component increased in duration as its decay was delayed; a slowing in decay rate also occurred and an earlier off-response was revealed. These effects were influenced by flash duration and the level of light adaptation. The late receptor potential was also recorded from the area centralis after clamping the retinal circulation at the optic disk. At moderate levels of light adaptation it was isolated from the c-wave and exhibited a rapid decay-phase. The behavior of the late RP in response to increases in flash intensity and duration paralled the behavior of the d.c. component. (Author).

An Analysis of the D.c. Component of the Local Electroretinogram in the Intact Eye of the Cat

An Analysis of the D.c. Component of the Local Electroretinogram in the Intact Eye of the Cat PDF Author: Roy H. Steinberg
Publisher:
ISBN:
Category :
Languages : en
Pages : 42

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Book Description
The local electroretinogram (LERG) was recorded with microelectrodes from the intact eye in response to focused spots and annuli delivered by a dual-beam ophthalmoscope. The d.c. component was readily isolated from the b-wave on the basis of a lower threshold, smaller summation area, and greater resistance to light adaptation, thereby supporting a hypothesis that separates these components. At high flash intensities the d.c. component increased in duration as its decay was delayed; a slowing in decay rate also occurred and an earlier off-response was revealed. These effects were influenced by flash duration and the level of light adaptation. The late receptor potential was also recorded from the area centralis after clamping the retinal circulation at the optic disk. At moderate levels of light adaptation it was isolated from the c-wave and exhibited a rapid decay-phase. The behavior of the late RP in response to increases in flash intensity and duration paralled the behavior of the d.c. component. (Author).

Reports

Reports PDF Author: Naval School of Aviation Medicine (U.S.)
Publisher:
ISBN:
Category :
Languages : en
Pages : 326

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Ganglion Cell Response Characteristics from the Area Centralis in the Intact Eye of the Cat

Ganglion Cell Response Characteristics from the Area Centralis in the Intact Eye of the Cat PDF Author: Roy Herbert Steinberg
Publisher:
ISBN:
Category : Retinal ganglion cells
Languages : en
Pages : 52

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Book Description
Ganglion cell responses were recorded with microelectrodes from the intact eye to focused spots and annuli of light delivered by a dual-beam ophthalmoscope. Only concentrically organized circular receptive fields were analysed. Thresholds for optimal center and surround stimuli were approximately equal, as were the latencies of on-responses from the center and surround. With whole-field stimulation center-dominance was a function of light intensity. Off-responses and center-surround interaction were observed with brief flashes (5 msec, 10 msec). With increases of flash duration the duration of the on-response did not increase by the full increment of the flash until the flashes were 50 to 80 msec. At high-flash intensities the on-response extended into the off-period and the off-response weakened and disappeared; it occurred with both on-excitation and on-inhibition and for the responses of both center and surround. These intensity effects were also studied in an intracellular recording; at high intensities, the rate of repolarization of the postsynaptic potential decreased, and the latency of repolarization was delayed. (Author).

Government Reports Index

Government Reports Index PDF Author:
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 864

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U.S. Government Research and Development Reports Index

U.S. Government Research and Development Reports Index PDF Author:
Publisher:
ISBN:
Category : Nuclear science abstracts
Languages : en
Pages : 1492

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Ryan's Retina E-Book

Ryan's Retina E-Book PDF Author: Charles P. Wilkinson
Publisher: Elsevier Health Sciences
ISBN: 0323401988
Category : Medical
Languages : en
Pages : 2893

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Book Description
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Features an expanded online video library highlighting the latest surgical techniques and new coverage of complications of vitreoretinal surgery. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology. Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.

Ophthalmic Literature

Ophthalmic Literature PDF Author:
Publisher:
ISBN:
Category : Ophthalmology
Languages : en
Pages : 822

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Author Index to Psychological Abstracts

Author Index to Psychological Abstracts PDF Author:
Publisher:
ISBN:
Category : Psychological abstracts
Languages : en
Pages : 914

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Retina

Retina PDF Author: David R. Hinton
Publisher: Elsevier Health Sciences
ISBN: 1455707376
Category : Medical
Languages : en
Pages : 2498

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Book Description
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice.