Author:
Publisher:
ISBN: 9780972709446
Category : Animal experimentation
Languages : en
Pages : 184

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Author: Devra Davis
Publisher: PublicAffairs
ISBN: 0465015689
Category : Medical
Languages : en
Pages : 562

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From the National Book Award finalist and author of "When Smoke Ran Like Water" comes this searing, haunting, and deeply personal account of how a major public health effort was diverted and distorted for private gain.

Author: Robert Proctor
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 372

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Written by a highly regarded historian of science, this meticulouly researched, eminently fair, and very provocative book attempts to answer the question: Why, given all the time and money spent on cancer research, can't we get consistent answers to the most fundamental questions about prevention and treatment?

Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 030904832X
Category : Medical
Languages : en
Pages : 448

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Book Description
Recently, World War II veterans have come forward to claim compensation for health effects they say were caused by their participation in chemical warfare experiments. In response, the Veterans Administration asked the Institute of Medicine to study the issue. Based on a literature review and personal testimony from more than 250 affected veterans, this new volume discusses in detail the development and chemistry of mustard agents and Lewisite followed by interesting and informative discussions about these substances and their possible connection to a range of health problems, from cancer to reproductive disorders. The volume also offers an often chilling historical examination of the use of volunteers in chemical warfare experiments by the U.S. militaryâ€"what the then-young soldiers were told prior to the experiments, how they were "encouraged" to remain in the program, and how they were treated afterward. This comprehensive and controversial book will be of importance to policymakers and legislators, military and civilian planners, officials at the Department of Veterans Affairs, military historians, and researchers.

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publisher: International Agency for Research on Cancer
ISBN: 9789283201526
Category : Medical
Languages : en
Pages : 0

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Book Description
This volume of the IARC Monographs provides evaluations of the consumption of red meat and the consumption of processed meat. Red meat refers to unprocessed mammalian muscle meat (e.g. beef, veal, pork, lamb) including that which may be minced or frozen. Processed meat refers to meat that has been transformed through salting, curing, fermentation, smoking or other processes to enhance flavor or improve preservation. Most processed meats contain pork or beef, but may also contain other meats including poultry and offal (e.g. liver) or meat by-products such as blood. Red meat contains proteins of high biological value, and important micronutrients such as B vitamins, iron (both free iron and haem iron), and zinc. Carcinogens, including heterocyclic aromatic amines and polycyclic aromatic hydrocarbons, can be produced by cooking of meat, with greatest amounts generated at high temperatures by pan-frying, grilling, or barbecuing. Meat processing such as curing and smoking can result in formation of carcinogenic chemicals including N-nitroso compounds and polycyclic aromatic hydrocarbons. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of the consumption of red meat and processed meat. The Working Group assessed more than 800 epidemiological studies that investigated the association of cancer (more than 15 types) with consumption of red meat or processed meat, including large cohorts in many countries, from several continents, with diverse ethnicities and diets.

Author: Raymond W. Ruddon
Publisher: Oxford University Press
ISBN: 0195175433
Category : Medical
Languages : en
Pages : 570

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Book Description
The fourth edition of this classic text provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It defines the fundamental pathophysiologic changes that occur in tumor tissue and in the host animal or patient. Each chapter discusses the historical development of a field, citing the key experimental advances to the present day, and evaluates the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well written and well illustrated, with schematic diagrams and actual research data to demonstrate points made in the text. There is also an extensive, up-to-date bibliography, making the book valuable to scientists, and to physicians, students, and nurses interested in the field of cancer biology. The topics covered include pathologic characterization of human tumors, epidemiology of human cancer, regulation of cell proliferation and differentiation, cellular and molecular phenotypic characteristics of the cancer cell, mechanisms of carcinogenesis, tumor initiation and promotion, viral carcinogenesis, oncogenes and oncogene products, growth factors, chromosomal alterations in cancer, mechanisms of tumor metastasis, host-tumor interactions, fundamental aspects of tumor immunology, and the advances in cancer cell biology that will lead to improved diagnosis and treatment of cancer in the future.

Author: Guy B. Faguet
Publisher: Springer Science & Business Media
ISBN: 1402036175
Category : Medical
Languages : en
Pages : 225

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Book Description
After reviewing the history of cancer and its impact on the population, Dr. Faguet exposes the antiquated notions that have driven cancer drug development, documents the stagnation in treatment outcomes despite major advances in cancer genomics and growing NCI budgets, and identifies the multiple factors that sustain the status quo. He shows that, contrary to frequent announcements of breakthroughs, our current cancer control model cannot eradicate most cancers and the reasons why. Significantly, this book also delineates a way forward via a shift from the discredited cell-kill approach of the past to an integrated, evidence-driven cancer control paradigm based on prevention, early diagnosis, and pharmacogenomics. The author's views are based on data published in mainstream scientific journals and other reliable references, 432 of which are cited.

Author: Samuel S. Epstein
Publisher: Baywood Publishing Company, Inc.
ISBN: 9780895033109
Category : Health & Fitness
Languages : en
Pages : 408

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Book Description
"Finally, Cancer-Gate tells you, the reader, how to fight back by arming yourself with the information you need to protect your family from everyday carcinogens, and how to become an activist in the war against cancer."--Jacket.

Author:
Publisher: Am Cncl on Science, Health
ISBN:
Category :
Languages : en
Pages : 26

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Author:
Publisher: Am Cncl on Science, Health
ISBN:
Category :
Languages : en
Pages : 15

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Book Description