Airway Mucus: Basic Mechanisms and Clinical Perspectives

Airway Mucus: Basic Mechanisms and Clinical Perspectives PDF Author: D.F. Rogers
Publisher: Springer Science & Business Media
ISBN: 9783764356910
Category : Medical
Languages : en
Pages : 408

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Book Description
Conceptually unsavoury, airway mucus is vital to homeostasis in the respiratory tract. In contrast, when abnormal, mucus contributes significantly to the pathophysiology of a number of severe bronchial diseases, including asthma, chronic bronchitis and cystic fibrosis. This volume provides wide ranging and in-depth coverage of the scientific and clinical aspects of airway mucus. It commences with introductory chapters which address the biochemical and molecular biological basis of airway mucus and continues with comprehensive coverage of the various physiological and rheological aspects of respiratory secretions. The clinical aspects of the topic are then considered, with chapters discussing the involvement of mucus secretions in bacterial infection and in hypersecretory diseases of the airway. The volume concludes with a discussion of the therapeutic aspects of the topic, both in terms of the possible approaches to the treatment of mucus hypersecretion and the interaction of these drugs with airway mucus. Written by leading experts in the field, each contribution provides a comprehensive review of its particular subject. Reflecting the latest advances in this important area of respiratory research, this volume will be of great interest to scientists and clinicians working in the field of airway secretions and related areas.

Airway Mucus: Basic Mechanisms and Clinical Perspectives

Airway Mucus: Basic Mechanisms and Clinical Perspectives PDF Author: D.F. Rogers
Publisher: Springer Science & Business Media
ISBN: 9783764356910
Category : Medical
Languages : en
Pages : 408

Get Book Here

Book Description
Conceptually unsavoury, airway mucus is vital to homeostasis in the respiratory tract. In contrast, when abnormal, mucus contributes significantly to the pathophysiology of a number of severe bronchial diseases, including asthma, chronic bronchitis and cystic fibrosis. This volume provides wide ranging and in-depth coverage of the scientific and clinical aspects of airway mucus. It commences with introductory chapters which address the biochemical and molecular biological basis of airway mucus and continues with comprehensive coverage of the various physiological and rheological aspects of respiratory secretions. The clinical aspects of the topic are then considered, with chapters discussing the involvement of mucus secretions in bacterial infection and in hypersecretory diseases of the airway. The volume concludes with a discussion of the therapeutic aspects of the topic, both in terms of the possible approaches to the treatment of mucus hypersecretion and the interaction of these drugs with airway mucus. Written by leading experts in the field, each contribution provides a comprehensive review of its particular subject. Reflecting the latest advances in this important area of respiratory research, this volume will be of great interest to scientists and clinicians working in the field of airway secretions and related areas.

Chronic Obstructive Pulmonary Disease Exacerbations

Chronic Obstructive Pulmonary Disease Exacerbations PDF Author: Jadwiga A. Wedzicha
Publisher: CRC Press
ISBN: 1420070878
Category : Medical
Languages : en
Pages : 476

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Book Description
Chronic Obstructive Pulmonary Disease Exacerbations covers the definition, diagnosis, epidemiology, mechanisms, and treatment associated with COPD exacerbations. This text also addresses imaging and how it plays a pivotal role in the diagnosis and study of exacerbations.Written by today's top experts, Chronic Obstructive Pulmonary Disease Exacerbat

Pocket Book of Hospital Care for Children

Pocket Book of Hospital Care for Children PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241548371
Category : Business & Economics
Languages : en
Pages : 442

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Book Description
The Pocket Book is for use by doctors nurses and other health workers who are responsible for the care of young children at the first level referral hospitals. This second edition is based on evidence from several WHO updated and published clinical guidelines. It is for use in both inpatient and outpatient care in small hospitals with basic laboratory facilities and essential medicines. In some settings these guidelines can be used in any facilities where sick children are admitted for inpatient care. The Pocket Book is one of a series of documents and tools that support the Integrated Managem.

Oxford Textbook of Critical Care

Oxford Textbook of Critical Care PDF Author: Webb
Publisher: Oxford University Press
ISBN: 0198855435
Category : Medical
Languages : en
Pages : 1961

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Book Description
Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Autogenic Drainage

Autogenic Drainage PDF Author: Chevaillier, Jean
Publisher: Servei de Publicacions de la Universitat Autònoma de Barcelona
ISBN: 8449043905
Category : Medical
Languages : en
Pages : 148

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Book Description
This work does not provide "recipes" or standardized solutions for the treatment of patients affected hypersecretion. The reader will find the book necessary ingredients to adapt to drain bronchial disease and the patient's condition, their needs and possibilities. Find relevant information ontology, anatomy, physiology and pulmonary ventilatory mechanics in order to facilitate understanding of the mechanisms involved in bronchial drainage techniques. It also delves into measurements of lung function and its implications. Explains the problems with obstruction and pulmonary physiotherapy assessment, as well as the bases of the bronchial drainage techniques. Not to mention the care of the upper airways. Acquire special mention specific principles of autogenic drainage, showing through performance curves partial expiratory flow-volume, the ability to modulate the flow and volume in the bronchial tree and selectively localize functional bronchial generations drain. Series of tips to standardize ventilation during inspiratory phase as well as the importance of correcting the shape of the rib cage. Explains the use of autogenic drainage in patients collaborators and collaborators, with a section dedicated to autogenic drainage in infants. The last chapters are devoted to explaining the specific physiology of cough with practical implications, special attention is given to inhalation therapy and finally being mentioned techniques as accessory respiratory reeducation and functional analysis, the importance of exercise and positioning, flexible gymnastics, relaxation, the use of oxygen and the rehabilitation effort through sport.

Severe Asthma

Severe Asthma PDF Author: Kian Fan Chung
Publisher: European Respiratory Society
ISBN: 1849841047
Category : Medical
Languages : en
Pages : 365

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Book Description
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

Cilia and Mucus

Cilia and Mucus PDF Author: Matthias Salathe
Publisher: CRC Press
ISBN: 1482270587
Category : Medical
Languages : en
Pages : 451

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Book Description
This book details advances in research regarding cilia, mucus, and mucociliary clearance, examining changes in mucus expression and goblet cell metaplasia, and assessing the ability of the mucociliary system to respond to abnormalities. Recognizes that cilia and dynein arms play pivotal roles in developing mammalian embryos! Examines the rol

Airway Remodeling

Airway Remodeling PDF Author: Peter Howarth
Publisher: CRC Press
ISBN: 9780429132582
Category : MEDICAL
Languages : en
Pages : 328

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Book Description
This landmark volume discusses the characteristics and impact of the remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth hypertrophy, and hyperplasias! Tracing the development and maintenance of bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic asthma, Airway Remodelingdescribes the contribution of inflammatory cells in the development of airway structural changes examines how pharmaceutical agents act and whether existing treatments modify or prevent remodeling in chronically inflamed asthmatic airways considers whether neural pathways initiate as well as contribute to the airway inflammatory cascade that leads to remodeling reviews the action of cytokines and growth factors on ASM signaling outlines novel approaches to regulating smooth muscle growth clarifies whether permanent ventilatory incapacity in asthma is caused by the uncoupling of the airway and the role of the lung parenchyma details high-resolution computerized tomography scan to measure the internal size of the airway at baseline, during challenge, or after bronchodilatation and more!Improving lung function and quality of life by reducing the need for emergency care, hospital admissions, and systemic steroid administration, Airway Remodeling is a superb reference for pulmonologists and respiratory system specialists; physiologists; pneumologists; allergists; pharmacologists; molecular, cellular, and lung biologists; and graduate and medical school students in these disciplines.

Summary Health Statistics for U.S. Adults

Summary Health Statistics for U.S. Adults PDF Author:
Publisher:
ISBN:
Category : Health surveys
Languages : en
Pages : 220

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Book Description