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Author: M. Baudry
Publisher: MIT Press
ISBN: 9780262024600
Category : Neuroplasticity
Languages : en
Pages : 368
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Book Description
This book, a follow-up to the editors' Synaptic Plasticity (MIT Press,1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Many neurons exhibit plasticity; that is, they can change structurally or functionally, often in a lasting way. Plasticity is evident in such diverse phenomena as learning and memory, brain development, drug tolerance, sprouting of axon terminals after a brain lesion, and various cellular forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression. This book, a follow-up to the editors' Synaptic Plasticity (MIT Press, 1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Contributors Yael Amitai, Michel Baudry, Theodore W. Berger, Pierre-Alain Buchs, A.K. Butler, Franck A. Chaillan, Gilbert A. Chauvet, Marie-Françoise Chesselet, Barry W. Connors, Taraneh Ghaffari, Jay R. Gibson, Ziv Gil, Michel Khrestchatisky, Dietmar Kuhl, Carole E. Landisman, Gilles Laurent, Jim-Shih Liaw, David J. Linden, Katrina MacLeod, Henry Markram, W.V. Morehouse, Dominique Muller, J.A. Napieralski, Santiago Rivera, François S. Roman, Bernard Soumireu-Mourat, Oswald Steward, Mark Stopfer, F.G. Szele, Richard F. Thompson, Nicolas Toni, Bernard Truchet, Misha Tsodyks, K. Uryu, Ascher Uziel, Christopher S. Wallace, Yun Wang, Michael Wehr, Paul F. Worley, Xiaping Xie
Author: M. Baudry
Publisher: MIT Press
ISBN: 9780262024600
Category : Neuroplasticity
Languages : en
Pages : 368
Get Book Here
Book Description
This book, a follow-up to the editors' Synaptic Plasticity (MIT Press,1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Many neurons exhibit plasticity; that is, they can change structurally or functionally, often in a lasting way. Plasticity is evident in such diverse phenomena as learning and memory, brain development, drug tolerance, sprouting of axon terminals after a brain lesion, and various cellular forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression. This book, a follow-up to the editors' Synaptic Plasticity (MIT Press, 1993), reports on the most recent trends in the field. The levels of analysis range from molecular to cellular and network, the unifying theme being the nature of the relationships between synaptic plasticity and information processing and storage. Contributors Yael Amitai, Michel Baudry, Theodore W. Berger, Pierre-Alain Buchs, A.K. Butler, Franck A. Chaillan, Gilbert A. Chauvet, Marie-Françoise Chesselet, Barry W. Connors, Taraneh Ghaffari, Jay R. Gibson, Ziv Gil, Michel Khrestchatisky, Dietmar Kuhl, Carole E. Landisman, Gilles Laurent, Jim-Shih Liaw, David J. Linden, Katrina MacLeod, Henry Markram, W.V. Morehouse, Dominique Muller, J.A. Napieralski, Santiago Rivera, François S. Roman, Bernard Soumireu-Mourat, Oswald Steward, Mark Stopfer, F.G. Szele, Richard F. Thompson, Nicolas Toni, Bernard Truchet, Misha Tsodyks, K. Uryu, Ascher Uziel, Christopher S. Wallace, Yun Wang, Michael Wehr, Paul F. Worley, Xiaping Xie
Author: Michael R. Kreutz
Publisher: Springer Science & Business Media
ISBN: 3709109310
Category : Medical
Languages : en
Pages : 611
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Book Description
This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.
Author: Federico Bermudez-Rattoni
Publisher: CRC Press
ISBN: 1420008412
Category : Psychology
Languages : en
Pages : 368
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Book Description
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Author: Daniel Laskowitz
Publisher: CRC Press
ISBN: 1498766579
Category : Medical
Languages : en
Pages : 412
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Book Description
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
Author: Wayne S. Sossin
Publisher: Elsevier
ISBN: 9780080932330
Category : Science
Languages : en
Pages : 450
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Book Description
This selection of reviews gives an up-to-date picture of memory research. Great progress has been made in identifying the memory trace at the molecular and cellular level and individual reviews address the major mechanisms by which changes in synaptic strength can persist. Exciting research at the systems level is also reviewed including the growing importance of changes in inhibitory interneurons and how they play a role in memory formation. Finally, reviews present cognitive and neurobiological models of human memory that explain, characterize and organize the act of memory within a coherent framework. * Provides an unique overview that covers all perspectives and methodological approaches to memory * Broad coverage of memory research from molecular to human studies in one source * Up-to-date reviews give the latest important ideas on memory formation
Author: Thomas Heinbockel
Publisher: BoD – Books on Demand
ISBN: 9535132334
Category : Medical
Languages : en
Pages : 224
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Book Description
Nerve cells form thousands of contact points, the synapses, to communicate information with other neurons and target cells. Synapses are sites for changes in brain function through modification of synaptic transmission termed synaptic plasticity. The study of synaptic plasticity has flourished over the years with the advancement of technical breakthroughs and is a timely scientific endeavor today just like it was several decades ago. This book contributes to our understanding of synaptic plasticity at the molecular, biochemical, and cellular systems and behavioral level and informs the reader about its clinical relevance. The book contains ten chapters in three sections: (1) "Mechanisms of Synaptic Plasticity," (2) "Neural Plasticity," and (3) "Plasticity and Neurological Diseases." The book provides detailed and current reviews in these different areas written by experts in their respective fields. The mechanisms of synaptic plasticity and its relation to neurological diseases are featured prominently as a recurring theme throughout most chapters. This book will be most useful for neuroscientists and other scientists alike and will contribute to the training of current and future students who find the plastic nervous system as fascinating as many generations before them.
Author:
Publisher:
ISBN: 9789535132349
Category :
Languages : en
Pages :
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Book Description
Author: J. David Sweatt
Publisher: Academic Press
ISBN: 0080959199
Category : Psychology
Languages : en
Pages : 362
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Book Description
This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding. More than 25% new content, particularly expanding the scope to include new findings in translational research. Unique in its depth of coverage of molecular and cellular mechanisms Extensive cross-referencing to Comprehensive Learning and Memory Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples
Author: Jacopo Lamanna
Publisher: Frontiers Media SA
ISBN: 2832536379
Category : Science
Languages : en
Pages : 117
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Book Description
Synapses represent a unique neuronal compartment specialized in communication. The morpho-functional investigation of the synapse has always been hindered by its tiny size and high density of molecular elements, but specific technological and methodological advances helped us to reduce these limitations. As the matter of fact, in recent years, we have witnessed the continuous development of new methods allowing measuring and controlling synaptic activation both in vitro and in vivo. These include new genetically encoded sensors of synaptic exo-endocytosis, but also engineered synaptic proteins able to inhibit the release of neurotransmitters. Furthermore, new promising tools allow changing the functional properties of synapses in a plasticity-like manner. All these methodological advances are likely to generate unprecedented knowledge about the dynamics of synaptic transmission and plasticity at several levels of the nervous system. Nevertheless, in most cases, the implementation of these new methods remains technically demanding, likely due to the high complexity of their operating principle. Hence, it would be worth refining and potentiating these tools in order to extend the range of experimental settings for their application.
Author: Helmut L. Haas
Publisher: Springer Science & Business Media
ISBN: 364273202X
Category : Medical
Languages : en
Pages : 219
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Book Description
This is the second time that I have had the honor of opening an interna tional symposium dedicated to the functions of the hippocampus here in Pecs. It was a pleasure to greet the participants in the hope that their valuable contributions will make this meeting a tradition in this town. As one of the hosts of the symposium, I had the sorrowful duty to remind you of the absence of a dear colleague, Professor Graham God dard. His tragic and untimely death represents the irreparable loss of both a friend and an excellent researcher. This symposium is dedicated to his memory. If I compare the topics of the lectures of this symposium with those of the previous one, a striking difference becomes apparent. A dominating tendency of the previous symposium was to attempt to define hippocam pal function or to offer data relevant to supporting or rejecting existing theoretical positions. No such tendency is reflected in the titles of the present symposium, in which most of the contributions deal with hip pocampal phenomena at the most elementary level. Electrical, biochemi cal, biophysical, and pharmacological events at the synaptic, membrane, or intracellular level are analyzed without raising the question of what kind of integral functions these elementary phenomena are a part of.
