The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism PDF Author: Anne Le
Publisher: Springer
ISBN: 331977736X
Category : Medical
Languages : en
Pages : 186

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Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism PDF Author: Anne Le
Publisher: Springer
ISBN: 331977736X
Category : Medical
Languages : en
Pages : 186

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Book Description
Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Cancer Incidence and Survival Among Children and Adolescents

Cancer Incidence and Survival Among Children and Adolescents PDF Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 194

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Book Description


Lymphoma

Lymphoma PDF Author: Anas Younes
Publisher: Springer Science & Business Media
ISBN: 1627034080
Category : Medical
Languages : en
Pages : 414

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Book Description
Recently, understanding the molecular pathogenesis of malignant lymphomas has led to improvement in the diagnostic precision and to the identification of a variety of molecular therapeutic targets. In addition, new drugs have been approved in the US and Europe, resulting in changes in the standard of care of several types of lymphoid malignancies. Comprehensive in scope and developed by a team of internationally renowned authors, Lymphoma: Diagnosis and Treatment provides a timely update on the most important advances in the biology, diagnosis, and therapy of lymphomas. As part of the Current Clinical Oncology series, Lymphoma: Diagnosis and Treatment will be of value to medical oncologists, hematologists, radiation oncologists, and all physicians involved in the care of patients with lymphoid malignancies.

Histiocytic Disorders

Histiocytic Disorders PDF Author: Oussama Abla
Publisher: Springer
ISBN: 3319596322
Category : Medical
Languages : en
Pages : 391

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Book Description
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.

Pediatric Surgery

Pediatric Surgery PDF Author: Prem Puri
Publisher: Springer
ISBN: 9783662435588
Category : Medical
Languages : en
Pages : 0

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Book Description
Pediatric Surgery provides an authoritative, up-to-date and comprehensive analysis of current practice in the field. It is divided into three topical volumes, with a total of seven sections focusing on general principles, newborn surgery, general pediatric surgery, tumor surgery, trauma, transplantation, and pediatric urology surgery. Detailed descriptions of surgical techniques and pre- and postoperative management are provided by experts from various parts of the world. The result is an international reference on the surgical management of both common and rare diseases of infants and children that will be an ideal source of information and guidance for pediatric surgeons, pediatric urologists, neonatologists, pediatricians, and all those seeking more detailed information on surgical conditions in children. The three topical volumes are as follows: General Principles and Newborn Surgery General Pediatric Surgery, Tumors, Trauma and Transplantation Pediatric Urology

PET/CT in Hodgkin’s Lymphoma

PET/CT in Hodgkin’s Lymphoma PDF Author: Irfan Kayani
Publisher: Springer
ISBN: 3319572253
Category : Medical
Languages : en
Pages : 100

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Book Description
This book is a pocket guide to the practice of PET/CT imaging of Hodgkin’s lymphoma. The role of PET/CT in Hodgkin’s lymphoma, the characteristic findings and patterns, and the advantages and limitations of this hybrid modality are all clearly described. In addition, information is provided on clinical presentation, diagnosis, staging, pathology, management, and conventional radiological imaging. A useful pictorial atlas is included at the end of the book. PET/CT in Hodgkin’s Lymphoma is published within the Springer series Clinicians' Guides to Radionuclide Hybrid Imaging, which is aimed at referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. Compiled under the auspices of the British Nuclear Medicine Society, the series is the joint work of many colleagues and professionals worldwide who share a common vision and purpose in promoting and supporting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.

Non-Hodgkin's Lymphoma in Childhood and Adolescence

Non-Hodgkin's Lymphoma in Childhood and Adolescence PDF Author: Oussama Abla
Publisher: Springer
ISBN: 3030117693
Category : Medical
Languages : en
Pages : 362

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Book Description
This text provides a state-of-the-art overview on Non-Hodgkin's lymphoma (NHL) in children and adolescents. The volume is divided into seven sections, each of which focuses on a critical component of pediatric NHL, including history and epidemiology, pathology and molecular biology, disease evaluation and response, common and rare sub-types of NHL, and current and novel treatment strategies. The text also comprehensively reviews the late effects of treatment, quality of patient life, and NHL treatment in countries with limited resources. Written by experts in the field, Non-Hodgkin's Lymphoma in Childhood and Adolescence is a valuable resource for clinicians and practitioners who treat children and adolescents with NHL.

Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues

Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues PDF Author: World Health Organization
Publisher: IARC
ISBN: 9789283224112
Category : Digestive organs
Languages : en
Pages : 360

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Book Description
This is the third volume in the new World Health Organization series on histological and genetic typing of tumours. Tumours of the haematopoietic and lymphoid tissues are covered. This was a collaborative project of the European Association for Haematolpathology and the Society for Haematopathology and others. The WHO classification is based on the principles defined in the Revised European-American Classification of Lymphoid Neoplasms (REAL) classification. Over 50 pathologists from around the world were involved in the project and proponents of all major lymphoma and leukaemia classifications have agreed to accept the WHO as the standard classification of haematological malignancies. So this classification represents the first true world wide concensus of haematologic malignancies. Colour photographs, magnetic resonance and ultrasound images and CT scans are included.

American Society of Hematology Self-Assessment Program

American Society of Hematology Self-Assessment Program PDF Author: Timothy Graubert
Publisher:
ISBN: 9780982843512
Category : Hematology
Languages : en
Pages : 637

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Book Description
Hematologists and others working in hematology-related fields need to stay current with the latest advances in the rapidly evolving disciplines of adult and pediatric hematology. The American Society of Hematology Self-Assessment Program (ASH-SAP) is the only complete, comprehensive, educational resource available that fulfills this need, while also providing thorough board and recertification preparation, as well as AMA PRA Category 1 Credit'.

Non-Hodgkin Lymphoma: New Insights for the Healthcare Professional: 2013 Edition

Non-Hodgkin Lymphoma: New Insights for the Healthcare Professional: 2013 Edition PDF Author:
Publisher: ScholarlyEditions
ISBN: 1481654667
Category : Medical
Languages : en
Pages : 106

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Book Description
Non-Hodgkin Lymphoma: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Genetics in a concise format. The editors have built Non-Hodgkin Lymphoma: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Genetics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Non-Hodgkin Lymphoma: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.