Advances in Network Electrophysiology

Advances in Network Electrophysiology PDF Author: Makoto Taketani
Publisher: Springer Science & Business Media
ISBN: 0387258582
Category : Medical
Languages : en
Pages : 488

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Book Description
Advances in Network Electrophysiology: Using Multi Electrode Arrays explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. It reviews the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons using multi-electrode arrays and in vitro preparations. In addition, it gives readers a sense of the applications made possible by these technological tools. This volume is the reference for researchers, industry, graduate students, and postdoctoral fellows in all areas of neuroscience, cognitive neuroscience, pharmaceutical science, and bioengineering.

Advances in Network Electrophysiology

Advances in Network Electrophysiology PDF Author: Makoto Taketani
Publisher: Springer Science & Business Media
ISBN: 0387258582
Category : Medical
Languages : en
Pages : 488

Get Book Here

Book Description
Advances in Network Electrophysiology: Using Multi Electrode Arrays explores methods for using electrophysiological techniques for monitoring the concurrent activity of ensembles of single neurons. It reviews the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons using multi-electrode arrays and in vitro preparations. In addition, it gives readers a sense of the applications made possible by these technological tools. This volume is the reference for researchers, industry, graduate students, and postdoctoral fellows in all areas of neuroscience, cognitive neuroscience, pharmaceutical science, and bioengineering.

In Vitro Neuronal Networks

In Vitro Neuronal Networks PDF Author: Michela Chiappalone
Publisher: Springer
ISBN: 3030111350
Category : Medical
Languages : en
Pages : 387

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Book Description
This book provides a comprehensive overview of the incredible advances achieved in the study of in vitro neuronal networks for use in basic and applied research. These cultures of dissociated neurons offer a perfect trade-off between complex experimental models and theoretical modeling approaches giving new opportunities for experimental design but also providing new challenges in data management and interpretation. Topics include culturing methodologies, neuroengineering techniques, stem cell derived neuronal networks, techniques for measuring network activity, and recent improvements in large-scale data analysis. The book ends with a series of case studies examining potential applications of these technologies.

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics PDF Author: Carl Faingold
Publisher: Academic Press
ISBN: 0124158641
Category : Medical
Languages : en
Pages : 537

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Book Description
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: - How the brain carries out important tasks via networks - How these networks interact in normal brain function - Major mechanisms that control network function - The interaction of the normal networks to produce more complex behaviors - How brain disorders can result from abnormal interactions - How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. - Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant - Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders - Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain - Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

The Functional Role of Critical Dynamics in Neural Systems

The Functional Role of Critical Dynamics in Neural Systems PDF Author: Nergis Tomen
Publisher: Springer
ISBN: 3030209652
Category : Medical
Languages : en
Pages : 301

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Book Description
This book offers a timely overview of theories and methods developed by an authoritative group of researchers to understand the link between criticality and brain functioning. Cortical information processing in particular and brain function in general rely heavily on the collective dynamics of neurons and networks distributed over many brain areas. A key concept for characterizing and understanding brain dynamics is the idea that networks operate near a critical state, which offers several potential benefits for computation and information processing. However, there is still a large gap between research on criticality and understanding brain function. For example, cortical networks are not homogeneous but highly structured, they are not in a state of spontaneous activation but strongly driven by changing external stimuli, and they process information with respect to behavioral goals. So far the questions relating to how critical dynamics may support computation in this complex setting, and whether they can outperform other information processing schemes remain open. Based on the workshop “Dynamical Network States, Criticality and Cortical Function", held in March 2017 at the Hanse Institute for Advanced Studies (HWK) in Delmenhorst, Germany, the book provides readers with extensive information on these topics, as well as tools and ideas to answer the above-mentioned questions. It is meant for physicists, computational and systems neuroscientists, and biologists.

Measuring Roots

Measuring Roots PDF Author: Stefano Mancuso
Publisher: Springer Science & Business Media
ISBN: 3642220673
Category : Science
Languages : en
Pages : 385

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Book Description
Roots represent half of the plant body – and arguably the more interesting half. Despite its obvious importance for the whole plant, until recently our knowledge of the root apparatus was very limited, mostly due to the inadequacy of the techniques available. Recent advances in the visualization and measurement of roots have resulted in significant progress in our understanding of root architecture, growth and behaviour. In this book international experts highlight the most advanced techniques, both lab and field methods, and discuss them in detail. Measuring Roots combines academic and practical aspects of this topic, making it a universal handbook for all researchers and others interested in root-measuring methods.

International Journal of Applied Sciences: Current and Future Research Trends (IJASCFRT)

International Journal of Applied Sciences: Current and Future Research Trends (IJASCFRT) PDF Author:
Publisher: International Journal of Applied Sciences: Current and Future Research Trends (IJASCFRT)
ISBN:
Category : Medical
Languages : en
Pages : 153

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Book Description


Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems

Neuronal Network Dynamics in 2D and 3D in vitro Neuroengineered Systems PDF Author: Monica Frega
Publisher: Springer
ISBN: 331930237X
Category : Technology & Engineering
Languages : en
Pages : 151

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Book Description
The book presents a new, powerful model of neuronal networks, consisting of a three-dimensional neuronal culture in which 3D neuronal networks are coupled to micro-electrode-arrays (MEAs). It discusses the main advantages of the three-dimensional system compared to its two-dimensional counterpart, and shows that the network dynamics, recorded during both spontaneous and stimulated activity, differs between the two models, with the 3D system being better able to emulate the in vivo behaviour of neural networks. The book offers an extensive analysis of the system, from the theoretical background, to its design and applications in neuro-pharmacological studies. Moreover, it includes a concise yet comprehensive introduction to both 2D and 3D neuronal networks coupled to MEAs, and discusses the advantages, limitations and challenges of their applications as cellular and tissue-like in vitro experimental model systems.

Correlated neuronal activity and its relationship to coding, dynamics and network architecture

Correlated neuronal activity and its relationship to coding, dynamics and network architecture PDF Author: Tatjana Tchumatchenko
Publisher: Frontiers E-books
ISBN: 2889193578
Category : Brain function
Languages : en
Pages : 237

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Book Description
Correlated activity in populations of neurons has been observed in many brain regions and plays a central role in cortical coding, attention, and network dynamics. Accurately quantifying neuronal correlations presents several difficulties. For example, despite recent advances in multicellular recording techniques, the number of neurons from which spiking activity can be simultaneously recorded remains orders magnitude smaller than the size of local networks. In addition, there is a lack of consensus on the distribution of pairwise spike cross correlations obtained in extracellular multi-unit recordings. These challenges highlight the need for theoretical and computational approaches to understand how correlations emerge and to decipher their functional role in the brain.

Estimating Functional Connectivity and Topology in Large-Scale Neuronal Assemblies

Estimating Functional Connectivity and Topology in Large-Scale Neuronal Assemblies PDF Author: Vito Paolo Pastore
Publisher: Springer Nature
ISBN: 3030590429
Category : Technology & Engineering
Languages : en
Pages : 98

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Book Description
This book describes a set of novel statistical algorithms designed to infer functional connectivity of large-scale neural assemblies. The algorithms are developed with the aim of maximizing computational accuracy and efficiency, while faithfully reconstructing both the inhibitory and excitatory functional links. The book reports on statistical methods to compute the most significant functional connectivity graph, and shows how to use graph theory to extract the topological features of the computed network. A particular feature is that the methods used and extended at the purpose of this work are reported in a fairly completed, yet concise manner, together with the necessary mathematical fundamentals and explanations to understand their application. Furthermore, all these methods have been embedded in the user-friendly open source software named SpiCoDyn, which is also introduced here. All in all, this book provides researchers and graduate students in bioengineering, neurophysiology and computer science, with a set of simplified and reduced models for studying functional connectivity in in silico biological neuronal networks, thus overcoming the complexity of brain circuits.

Basic Electrophysiological Methods

Basic Electrophysiological Methods PDF Author: Ellen Covey
Publisher: Oxford University Press
ISBN: 0199342547
Category : Medical
Languages : en
Pages : 241

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Book Description
Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.