Methods in Molecular Biophysics

Methods in Molecular Biophysics PDF Author: Nathan R. Zaccai
Publisher: Cambridge University Press
ISBN: 1108508804
Category : Science
Languages : en
Pages : 710

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Book Description
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.

Methods in Molecular Biophysics

Methods in Molecular Biophysics PDF Author: Nathan R. Zaccai
Publisher: Cambridge University Press
ISBN: 1108508804
Category : Science
Languages : en
Pages : 710

Get Book Here

Book Description
Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.

Advances in Molecular Biophysics

Advances in Molecular Biophysics PDF Author: Keira O'Donnell
Publisher:
ISBN: 9781641162784
Category : Science
Languages : en
Pages : 241

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Book Description
Molecular biophysics is an interdisciplinary domain of research which combines the principles of physics, chemistry, mathematics, engineering and biology. It aims to explain bimolecular systems and biological functions in terms of dynamic behaviour, molecular structure and structural organization. This field seeks to understand biological processes and functions at different levels of complexity, such as from viruses to small living systems, and from single molecules to supramolecular structures. The study of allosteric interactions, molecular forces, molecular associations, cable theory and Brownian motion are also addressed by molecular biophysics. Procedures that enable imaging and manipulation of living structures aid research in molecular biophysics. Spectroscopic techniques comprising of laser Raman, FT-NMR, FT-infrared, spin label electron spin resonance, etc. are widely used to understand structural dynamics of biomolecules and their intermolecular interactions. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of molecular biophysics. The various advancements in this field are glanced at and their applications as well as ramifications are looked at in detail. Students, researchers, experts and all associated with molecular biophysics will benefit alike from this book.

Pulling Rabbits Out of Hats

Pulling Rabbits Out of Hats PDF Author: David Wollkind
Publisher: CRC Press
ISBN: 9781003195603
Category : Mathematics
Languages : en
Pages : 538

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Book Description
"Pulling Rabbits Out of Hats: Using Mathematical Modeling in the Material, Biophysical, Fluid Mechanical, and Chemical Sciences focuses on those assumptions made during applied mathematical modeling in which the phenomenological data and the model predictions are self-consistent. This comprehensive reference demonstrates how to employ a variety of mathematical techniques to quantify a number of problems from the material, biophysical, fluid mechanical, and chemical sciences. In doing so, methodology of modelling, analysis, and result generation are all covered"--

Molecular Biophysics

Molecular Biophysics PDF Author: Michel Daune
Publisher: Oxford University Press, USA
ISBN: 9780198577836
Category : Science
Languages : en
Pages : 499

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Book Description
This new textbook offers a comprehensive introduction to the molecular physics of biological systems: it seeks to explain how the laws and concepts of physics apply to the living world at the molecular and subcellular level, with an emphasis on electrical and dynamical behaviour. The book is organized into five parts: * conformation of biopolymers * dynamics of biopolymers * hydration of biopolymers * biopolymers as polyelectrolytes *association between molecules The author adopts a multi-disciplinary approach and limits mathematics only to what is strictly necessary for the development of the subject. The text should be suitable for students from a wide range of backgrounds in biology, physics or chemistry taking advanced courses in molecular biophysics or biophysical chemistry.

Molecular Biophysics for the Life Sciences

Molecular Biophysics for the Life Sciences PDF Author: Norma Allewell
Publisher: Springer Science & Business Media
ISBN: 1461485487
Category : Science
Languages : en
Pages : 401

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Book Description
This volume provides an overview of the development and scope of molecular biophysics and in-depth discussions of the major experimental methods that enable biological macromolecules to be studied at atomic resolution. It also reviews the physical chemical concepts that are needed to interpret the experimental results and to understand how the structure, dynamics, and physical properties of biological macromolecules enable them to perform their biological functions. Reviews of research on three disparate biomolecular machines—DNA helicases, ATP synthases, and myosin--illustrate how the combination of theory and experiment leads to new insights and new questions.

Advanced Techniques in Biophysics

Advanced Techniques in Biophysics PDF Author: José Luis R. Arrondo
Publisher: Springer Science & Business Media
ISBN: 3540307869
Category : Science
Languages : en
Pages : 290

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Book Description
Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.

Advances in Protein Molecular and Structural Biology Methods

Advances in Protein Molecular and Structural Biology Methods PDF Author: Timir Tripathi
Publisher: Academic Press
ISBN: 0323902650
Category : Science
Languages : en
Pages : 716

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Book Description
Advances in Protein Molecular and Structural Biology Methods offers a complete overview of the latest tools and methods applicable to the study of proteins at the molecular and structural level. The book begins with sections exploring tools to optimize recombinant protein expression and biophysical techniques such as fluorescence spectroscopy, NMR, mass spectrometry, cryo-electron microscopy, and X-ray crystallography. It then moves towards computational approaches, considering structural bioinformatics, molecular dynamics simulations, and deep machine learning technologies. The book also covers methods applied to intrinsically disordered proteins (IDPs)followed by chapters on protein interaction networks, protein function, and protein design and engineering. It provides researchers with an extensive toolkit of methods and techniques to draw from when conducting their own experimental work, taking them from foundational concepts to practical application. - Presents a thorough overview of the latest and emerging methods and technologies for protein study - Explores biophysical techniques, including nuclear magnetic resonance, X-ray crystallography, and cryo-electron microscopy - Includes computational and machine learning methods - Features a section dedicated to tools and techniques specific to studying intrinsically disordered proteins

Single-Molecule Cellular Biophysics

Single-Molecule Cellular Biophysics PDF Author: Mark C. Leake
Publisher: Cambridge University Press
ISBN: 1107005833
Category : Science
Languages : en
Pages : 291

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Book Description
Indispensable textbook for undergraduate students in the physical and life sciences, unravelling the inner workings of the cell.

The Resolution Revolution: Recent Advances In cryoEM

The Resolution Revolution: Recent Advances In cryoEM PDF Author:
Publisher: Academic Press
ISBN: 0128054352
Category : Science
Languages : en
Pages : 488

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Book Description
cryoEM, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods and new developments in recording images, the creation, evaluation and validation of 3D maps from the images, model building into maps and refinement of the resulting atomic structures, and applications of essentially single particle methods to helical structures and to sub-tomogram averaging. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers research methods that determine the structures of biological molecules, a vital step for understanding their function - Contains the technical developments underpinning the advances of cryoEM and captures the exciting insights that have resulted

Biochemistry, Biophysics, and Molecular Chemistry

Biochemistry, Biophysics, and Molecular Chemistry PDF Author: Francisco Torrens
Publisher: CRC Press
ISBN: 1000008320
Category : Medical
Languages : en
Pages : 211

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Book Description
Biochemistry, Biophysics, and Molecular Chemistry: Applied Research and Interactions provides the background needed in biophysics and molecular chemistry and offers a great deal of advanced biophysical knowledge. It emphasizes the growing interrelatedness of molecular chemistry and biochemistry, and acquaints one with experimental methods of both disciplines. This book addresses some of the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry. Topics include scientific integrity and ethics in the field; clinical translational research in cancer, diabetes, and cardiovascular disease; emerging drugs to treat neurodegenerative diseases; swine, avian, and human flu; the use of big data in artificial knowledge in the field; bioinformatic insights on molecular chemistry; and much more.