Author: Francisco Gonzalez-Lima
Publisher: Springer Science & Business Media
ISBN: 9401127123
Category : Medical
Languages : en
Pages : 539
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Book Description
In recent years, revolutionary technical advances have permitted neuroscientists to map the functioning of the brain in exquisite detail. Of interest are the new techniques that visually display cell energy metabolism which is coupled to functional brain activity in behaving animals. This is the first book dealing with the application of 2-deoxyglucose and related metabolic mapping techniques for brain imaging of behavioral and learning functions. Quantitative autoradiographic techniques based on the use of exogenous markers include radiolabeled glucose and its analogs, especially 2-deoxyglucose and fluorodeoxyglucose. Other mapping techniques are based on the histochemical staining of endogenous metabolic markers such as cytochrome oxidase, as well as immunohistochemistry for expression of c-fos genes. In spite of the great potential capabilities of the new imaging techniques, relatively few neuroscientists are using this approach to study brain functions related to behavior. There is a need to review state-of-the-art applications of these methods in behavioral neuroscience, and to formulate recommendations for future research in this area. This book is intended to fulfill these needs by bringing together leading neuroscientists using metabolic mapping approaches to elucidate brain mechanisms of behavior. Discussions are not limited to one animal species, but they cover a broad range of vertebrates with unique behavioral capabilities.
Author: National Library of Medicine (U.S.)
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 690
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Book Description
First multi-year cumulation covers six years: 1965-70.
Author: Friedrich T. Sommer
Publisher: MIT Press
ISBN: 9780262194815
Category : Computers
Languages : en
Pages : 318
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Book Description
An overview of theoretical and computational approaches to neuroimaging.
Author: Francisco Gonzalez-Lima
Publisher: Springer Science & Business Media
ISBN: 1475799365
Category : Medical
Languages : en
Pages : 294
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Book Description
This book is based on an international symposium titled "Cytochrome oxidase in energy metabolism and Alzheimer's disease," held as a satellite to the 27th meeting of the Society for Neuroscience, New Orleans, 1997. The symposium was dedicated in honor of Dr. Margaret T. T. Wong-Riley because, in our opinion, the cytochrome oxidase histo chemical method introduced by Dr. Wong-Riley in 1979 was the most significant break through to map energy metabolism in the entire brain since the 2-deoxyglucose method introduced by Dr. Louis Sokoloff and colleagues in 1977. Both of these metabolic map ping techniques have made monumental contributions to brain research by allowing an integral view of brain activity. They have also developed into various specialized tech niques, including applications to the human brain. One of these new applications, which is described in detail in this book, is the quantitative cytochrome oxidase cytochemical method used to study Alzheimer's disease. The objective of this book is to describe the role of cytochrome oxidase in neuronal metabolism and Alzheimer's disease. Whether genetic or environmental, the pathogenesis of Alzheimer's disease involves a cascade of multiple intracellular events, eventually re sulting in failure of oxidative energy metabolism. Could impairment of cytochrome oxi dase in energy metabolism initiate the degenerative process? Cytochrome oxidase function and dysfunction are discussed in relationship to neuronal energy metabolism, neurodegen eration, and Alzheimer's disease. The book is made up of 10 chapters, divided into three major parts.
Author: Richard J. Davidson
Publisher: Oxford University Press
ISBN: 0190285311
Category : Psychology
Languages : en
Pages : 306
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Book Description
This unique volume focuses on the relationship between basic research in emotion and emotional dysfunction in depression and anxiety. Each chapter is authored by a highly regarded scientist who looks at both psychological and biological implications of research relevant to psychiatrists and psychologists. And following each chapter is engaging commentary that raises questions, illuminates connections with other bodies of work, and provides points of integration across different research traditions. Topics range from stress, cognitive functioning, and personality to affective style and behavioral inhibition, and the book as a whole has significant implications for understanding and treating anxiety disorders.
Author: Jeffery A. Winer
Publisher: Springer Science & Business Media
ISBN: 1441900748
Category : Science
Languages : en
Pages : 711
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Book Description
There has been substantial progress in understanding the contributions of the auditory forebrain to hearing, sound localization, communication, emotive behavior, and cognition. The Auditory Cortex covers the latest knowledge about the auditory forebrain, including the auditory cortex as well as the medial geniculate body in the thalamus. This book will cover all important aspects of the auditory forebrain organization and function, integrating the auditory thalamus and cortex into a smooth, coherent whole. Volume One covers basic auditory neuroscience. It complements The Auditory Cortex, Volume 2: Integrative Neuroscience, which takes a more applied/clinical perspective.
Author: Stefan M Brudzynski
Publisher: Academic Press
ISBN: 0080923372
Category : Psychology
Languages : en
Pages : 551
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Book Description
Handbook of Mammalian Vocalization is designed as a broad and comprehensive, but well-balanced book, written from the neuroscience point of view in the broad sense of this term. This well-illustrated Handbook pays particular attention to systematically organized details but also to the explanatory style of the text and internal cohesiveness of the content, so the successive chapters gradually develop a consistent story without losing the inherent complexity. Studies from many species are included, however rodents dominate, as most of the brain investigations were done on these species. The leading idea of the Handbook is that vocalizations evolved as highly adaptive specific signals, which are selectively picked up by the brain. The brain serves as a receptor and behavioural amplifier. Brain systems will be described, which allow vocal signals rapidly changing the entire state of the organism and trigger vital biological responses, usually also with accompanying emission of vocalizations. Integrative brain functions leading to vocal outcome will be described, along with the vocalization generators and motor output to larynx and other supportive motor subsystems. The last sections of the Handbook explains bioacoustic structure of vocalizations, present understanding of information coding, and origins of the complex semiotic/ semantic content of vocalizations in social mammals. The Handbook is a major source of information for professionals from many fields, with a neuroscience approach as a common denominator. The handbook provides consistent and unified understanding of all major aspects of vocalization in a monographic manner, and at the same time, gives an encyclopaedic overview of major topics associated with vocalization from molecular/ cellular level to behavior and cognitive processing. It is written in a strictly scientific way but clear enough to serve not only for specialized researchers in different fields of neuroscience but also for academic teachers of neuroscience, including behavioural neuroscience, affective neuroscience, clinical neuroscience, neuroethology, biopsychology, neurolingusitics, speech pathology, and other related fields, and also for research fellows, graduate and other advanced students, who widely need such a source publication. - The first comprehensive handbook on what we know about vocalization in Mammalians - Carefully edited, the handbook provides an integrated overview of the area - International list of highly regarded contributors, including Jaak Pankseep (Washington State University), David McFarland (Oxford), John D. Newman (NIH ? Unit on Developmental Neuroethology), Gerd Poeggel (Leipzig), Shiba Keisuke (Chiba City, Japan), and others, tightly edited by a single, well regarded editor who has edited a special issue in Behavioral Brain Research on the topic before
Author: H Fastl
Publisher: World Scientific
ISBN: 9814549266
Category :
Languages : en
Pages : 604
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Book Description
The main aim of the symposium on the hearing system is to provide a forum in which data, ideas and models from both the physiological and psychoacoustical standpoints can be presented and discussed. Apart from those areas traditionally covered by such meetings, two areas with important recent advances have been included, viz, development and regeneration. The present volume will be of interest to all scientists working in the field of auditory research.
Author: Tomris Özben
Publisher: Springer Science & Business Media
ISBN: 1475729073
Category : Science
Languages : en
Pages : 390
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Book Description
There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.
Author: Jonathan K. Foster
Publisher: Psychology Press
ISBN: 9780863776564
Category : Medical
Languages : en
Pages : 248
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Book Description
The collection of papers presented covers a range of stimulating memory-related topics, ranging from a study of autobiographical memory, working memory, an investigation into "medial temporal lobe" versus "diencephalic" amnesia (combined with an evaluation of different forms of image analysis), neuroimaging and "psychogenic amnesia", an empirical review paper, a study of incidental retrieval in the context of encoding, a critique of contemporary neuroimaging research (with specific reference to the anatomical lesion literature), a neuroimaging study of memory using event-related functional neuroimaging, a paper concerned with the interpretation and meaning of psychological data obtained from contemporary neuroimaging methodologies, to a submission which questions the view that anatomically "bigger" structures necessarily subserve memory "better". All the contributors to this special edition acknowledge the the intrinsically highly dynamic nature of this field. However, taken together, these papers provide an overview of where neuroimaging data currently place us, with respect to the issue of the neural mediation of memory, and concerning our theorizing about the cognitive architecture of memory processes. Such a review is important and timely: this research perspective, unavailable until just few years go, has already made a considerable contribution to our level of understanding, and, if harnessed appropriately, has considerably more to offer in the future.
