Advanced Data Analysis in Neuroscience

Advanced Data Analysis in Neuroscience PDF Author: Daniel Durstewitz
Publisher: Springer
ISBN: 3319599763
Category : Medical
Languages : en
Pages : 308

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Book Description
This book is intended for use in advanced graduate courses in statistics / machine learning, as well as for all experimental neuroscientists seeking to understand statistical methods at a deeper level, and theoretical neuroscientists with a limited background in statistics. It reviews almost all areas of applied statistics, from basic statistical estimation and test theory, linear and nonlinear approaches for regression and classification, to model selection and methods for dimensionality reduction, density estimation and unsupervised clustering. Its focus, however, is linear and nonlinear time series analysis from a dynamical systems perspective, based on which it aims to convey an understanding also of the dynamical mechanisms that could have generated observed time series. Further, it integrates computational modeling of behavioral and neural dynamics with statistical estimation and hypothesis testing. This way computational models in neuroscience are not only explanatory frameworks, but become powerful, quantitative data-analytical tools in themselves that enable researchers to look beyond the data surface and unravel underlying mechanisms. Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered. "Computational neuroscience is essential for integrating and providing a basis for understanding the myriads of remarkable laboratory data on nervous system functions. Daniel Durstewitz has excellently covered the breadth of computational neuroscience from statistical interpretations of data to biophysically based modeling of the neurobiological sources of those data. His presentation is clear, pedagogically sound, and readily useable by experts and beginners alike. It is a pleasure to recommend this very well crafted discussion to experimental neuroscientists as well as mathematically well versed Physicists. The book acts as a window to the issues, to the questions, and to the tools for finding the answers to interesting inquiries about brains and how they function." Henry D. I. Abarbanel Physics and Scripps Institution of Oceanography, University of California, San Diego “This book delivers a clear and thorough introduction to sophisticated analysis approaches useful in computational neuroscience. The models described and the examples provided will help readers develop critical intuitions into what the methods reveal about data. The overall approach of the book reflects the extensive experience Prof. Durstewitz has developed as a leading practitioner of computational neuroscience. “ Bruno B. Averbeck

Advanced Data Analysis in Neuroscience

Advanced Data Analysis in Neuroscience PDF Author: Daniel Durstewitz
Publisher: Springer
ISBN: 3319599763
Category : Medical
Languages : en
Pages : 308

Get Book Here

Book Description
This book is intended for use in advanced graduate courses in statistics / machine learning, as well as for all experimental neuroscientists seeking to understand statistical methods at a deeper level, and theoretical neuroscientists with a limited background in statistics. It reviews almost all areas of applied statistics, from basic statistical estimation and test theory, linear and nonlinear approaches for regression and classification, to model selection and methods for dimensionality reduction, density estimation and unsupervised clustering. Its focus, however, is linear and nonlinear time series analysis from a dynamical systems perspective, based on which it aims to convey an understanding also of the dynamical mechanisms that could have generated observed time series. Further, it integrates computational modeling of behavioral and neural dynamics with statistical estimation and hypothesis testing. This way computational models in neuroscience are not only explanatory frameworks, but become powerful, quantitative data-analytical tools in themselves that enable researchers to look beyond the data surface and unravel underlying mechanisms. Interactive examples of most methods are provided through a package of MatLab routines, encouraging a playful approach to the subject, and providing readers with a better feel for the practical aspects of the methods covered. "Computational neuroscience is essential for integrating and providing a basis for understanding the myriads of remarkable laboratory data on nervous system functions. Daniel Durstewitz has excellently covered the breadth of computational neuroscience from statistical interpretations of data to biophysically based modeling of the neurobiological sources of those data. His presentation is clear, pedagogically sound, and readily useable by experts and beginners alike. It is a pleasure to recommend this very well crafted discussion to experimental neuroscientists as well as mathematically well versed Physicists. The book acts as a window to the issues, to the questions, and to the tools for finding the answers to interesting inquiries about brains and how they function." Henry D. I. Abarbanel Physics and Scripps Institution of Oceanography, University of California, San Diego “This book delivers a clear and thorough introduction to sophisticated analysis approaches useful in computational neuroscience. The models described and the examples provided will help readers develop critical intuitions into what the methods reveal about data. The overall approach of the book reflects the extensive experience Prof. Durstewitz has developed as a leading practitioner of computational neuroscience. “ Bruno B. Averbeck

Analyzing Neural Time Series Data

Analyzing Neural Time Series Data PDF Author: Mike X Cohen
Publisher: MIT Press
ISBN: 0262019876
Category : Psychology
Languages : en
Pages : 615

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Book Description
A comprehensive guide to the conceptual, mathematical, and implementational aspects of analyzing electrical brain signals, including data from MEG, EEG, and LFP recordings. This book offers a comprehensive guide to the theory and practice of analyzing electrical brain signals. It explains the conceptual, mathematical, and implementational (via Matlab programming) aspects of time-, time-frequency- and synchronization-based analyses of magnetoencephalography (MEG), electroencephalography (EEG), and local field potential (LFP) recordings from humans and nonhuman animals. It is the only book on the topic that covers both the theoretical background and the implementation in language that can be understood by readers without extensive formal training in mathematics, including cognitive scientists, neuroscientists, and psychologists. Readers who go through the book chapter by chapter and implement the examples in Matlab will develop an understanding of why and how analyses are performed, how to interpret results, what the methodological issues are, and how to perform single-subject-level and group-level analyses. Researchers who are familiar with using automated programs to perform advanced analyses will learn what happens when they click the “analyze now” button. The book provides sample data and downloadable Matlab code. Each of the 38 chapters covers one analysis topic, and these topics progress from simple to advanced. Most chapters conclude with exercises that further develop the material covered in the chapter. Many of the methods presented (including convolution, the Fourier transform, and Euler's formula) are fundamental and form the groundwork for other advanced data analysis methods. Readers who master the methods in the book will be well prepared to learn other approaches.

Mathematical and Theoretical Neuroscience

Mathematical and Theoretical Neuroscience PDF Author: Giovanni Naldi
Publisher: Springer
ISBN: 3319682970
Category : Mathematics
Languages : en
Pages : 255

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Book Description
This volume gathers contributions from theoretical, experimental and computational researchers who are working on various topics in theoretical/computational/mathematical neuroscience. The focus is on mathematical modeling, analytical and numerical topics, and statistical analysis in neuroscience with applications. The following subjects are considered: mathematical modelling in Neuroscience, analytical and numerical topics; statistical analysis in Neuroscience; Neural Networks; Theoretical Neuroscience. The book is addressed to researchers involved in mathematical models applied to neuroscience.

MATLAB for Neuroscientists

MATLAB for Neuroscientists PDF Author: Pascal Wallisch
Publisher: Academic Press
ISBN: 0123838371
Category : Psychology
Languages : en
Pages : 571

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Book Description
MATLAB for Neuroscientists serves as the only complete study manual and teaching resource for MATLAB, the globally accepted standard for scientific computing, in the neurosciences and psychology. This unique introduction can be used to learn the entire empirical and experimental process (including stimulus generation, experimental control, data collection, data analysis, modeling, and more), and the 2nd Edition continues to ensure that a wide variety of computational problems can be addressed in a single programming environment. This updated edition features additional material on the creation of visual stimuli, advanced psychophysics, analysis of LFP data, choice probabilities, synchrony, and advanced spectral analysis. Users at a variety of levels—advanced undergraduates, beginning graduate students, and researchers looking to modernize their skills—will learn to design and implement their own analytical tools, and gain the fluency required to meet the computational needs of neuroscience practitioners. - The first complete volume on MATLAB focusing on neuroscience and psychology applications - Problem-based approach with many examples from neuroscience and cognitive psychology using real data - Illustrated in full color throughout - Careful tutorial approach, by authors who are award-winning educators with strong teaching experience

Case Studies in Neural Data Analysis

Case Studies in Neural Data Analysis PDF Author: Mark A. Kramer
Publisher: MIT Press
ISBN: 0262529378
Category : Science
Languages : en
Pages : 385

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Book Description
A practical guide to neural data analysis techniques that presents sample datasets and hands-on methods for analyzing the data. As neural data becomes increasingly complex, neuroscientists now require skills in computer programming, statistics, and data analysis. This book teaches practical neural data analysis techniques by presenting example datasets and developing techniques and tools for analyzing them. Each chapter begins with a specific example of neural data, which motivates mathematical and statistical analysis methods that are then applied to the data. This practical, hands-on approach is unique among data analysis textbooks and guides, and equips the reader with the tools necessary for real-world neural data analysis. The book begins with an introduction to MATLAB, the most common programming platform in neuroscience, which is used in the book. (Readers familiar with MATLAB can skip this chapter and might decide to focus on data type or method type.) The book goes on to cover neural field data and spike train data, spectral analysis, generalized linear models, coherence, and cross-frequency coupling. Each chapter offers a stand-alone case study that can be used separately as part of a targeted investigation. The book includes some mathematical discussion but does not focus on mathematical or statistical theory, emphasizing the practical instead. References are included for readers who want to explore the theoretical more deeply. The data and accompanying MATLAB code are freely available on the authors' website. The book can be used for upper-level undergraduate or graduate courses or as a professional reference. A version of this textbook with all of the examples in Python is available on the MIT Press website.

Data-Driven Computational Neuroscience

Data-Driven Computational Neuroscience PDF Author: Concha Bielza
Publisher: Cambridge University Press
ISBN: 110849370X
Category : Computers
Languages : en
Pages : 709

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Book Description
Trains researchers and graduate students in state-of-the-art statistical and machine learning methods to build models with real-world data.

Guide to Research Techniques in Neuroscience

Guide to Research Techniques in Neuroscience PDF Author: Matt Carter
Publisher: Academic Press
ISBN: 0323915612
Category : Medical
Languages : en
Pages : 416

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Book Description
Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step

Analysis of Neural Data

Analysis of Neural Data PDF Author: Robert E. Kass
Publisher: Springer
ISBN: 1461496020
Category : Medical
Languages : en
Pages : 663

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Book Description
Continual improvements in data collection and processing have had a huge impact on brain research, producing data sets that are often large and complicated. By emphasizing a few fundamental principles, and a handful of ubiquitous techniques, Analysis of Neural Data provides a unified treatment of analytical methods that have become essential for contemporary researchers. Throughout the book ideas are illustrated with more than 100 examples drawn from the literature, ranging from electrophysiology, to neuroimaging, to behavior. By demonstrating the commonality among various statistical approaches the authors provide the crucial tools for gaining knowledge from diverse types of data. Aimed at experimentalists with only high-school level mathematics, as well as computationally-oriented neuroscientists who have limited familiarity with statistics, Analysis of Neural Data serves as both a self-contained introduction and a reference work.

Advanced Imaging Methods in Neuroscience

Advanced Imaging Methods in Neuroscience PDF Author: João O. Malva
Publisher: Frontiers Media SA
ISBN: 2889717259
Category : Science
Languages : en
Pages : 498

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Book Description


The Statistical Physics of Data Assimilation and Machine Learning

The Statistical Physics of Data Assimilation and Machine Learning PDF Author: Henry D. I. Abarbanel
Publisher: Cambridge University Press
ISBN: 1009021702
Category : Science
Languages : en
Pages : 208

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Book Description
Data assimilation is a hugely important mathematical technique, relevant in fields as diverse as geophysics, data science, and neuroscience. This modern book provides an authoritative treatment of the field as it relates to several scientific disciplines, with a particular emphasis on recent developments from machine learning and its role in the optimisation of data assimilation. Underlying theory from statistical physics, such as path integrals and Monte Carlo methods, are developed in the text as a basis for data assimilation, and the author then explores examples from current multidisciplinary research such as the modelling of shallow water systems, ocean dynamics, and neuronal dynamics in the avian brain. The theory of data assimilation and machine learning is introduced in an accessible and unified manner, and the book is suitable for undergraduate and graduate students from science and engineering without specialized experience of statistical physics.