Author: Monica Castiglione
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Adjuvant Therapy for Breast Cancer
Author: Monica Castiglione
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Publisher: Springer Science & Business Media
ISBN: 0387751157
Category : Medical
Languages : en
Pages : 483
Book Description
Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.
Surgical Management of Advanced Pelvic Cancer
Author: Desmond C. Winter
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324
Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Publisher: John Wiley & Sons
ISBN: 1119518407
Category : Medical
Languages : en
Pages : 324
Book Description
An innovative guide to the practice of pelvic exenterative surgery for the management of advanced pelvic neoplasms Exenterative surgery plays an important role in the management of advanced pelvic cancer. However, while a large body of evidence regarding outcomes following pelvic exenteration now exists, practical strategies and management options remain unclear. Surgical Management of Advanced Pelvic Cancer addresses this problem by assembling world-leaders in the field to provide insights into the latest techniques and best practices. It includes detailed coverage of: Surgical anatomy Operative approaches and exenterative techniques Reconstruction options Current evidence on survival and quality of life outcomes Featuring essential information for those managing patients with advanced pelvic neoplasms, Surgical Management of Advanced Pelvic Cancer consolidates the latest data and practical advice in one indispensable guide.
Clinical Radiation Oncology
Author: Leonard L. Gunderson, MD, MS, FASTRO
Publisher: Elsevier Health Sciences
ISBN: 0323240984
Category : Medical
Languages : en
Pages : 2253
Book Description
Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Publisher: Elsevier Health Sciences
ISBN: 0323240984
Category : Medical
Languages : en
Pages : 2253
Book Description
Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites - for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Four videos accessible on Expert Consult include Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma. Thirty all-new anatomy drawings increase your visual understanding. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Adjuvant Chemotherapy
Author: Yasushi Tsuji
Publisher:
ISBN: 9781536139334
Category : Chemotherapy
Languages : en
Pages : 0
Book Description
In the age of constant knowledge via computer accessibility, the effort to write a book on adjuvant chemotherapy may seem almost futile. However, the information seen online is usually fragmented, without context, and often somewhat unreliable. This book aims to provide a handy and reliable reference to better understand both the current situation and the future directions in the field of adjuvant chemotherapy. Its ten chapters covering major cancers were written by prominent researchers with decades of experience in clinical settings as well as in related fields of research. Owing mostly to the development of novel cancer drugs, cytotoxic agents, targeting agents and immune check point inhibitors, the prognosis of all cancers has markedly improved. On the other hand, determining the best way to use these drugs is becoming more and more complicated, and most patients after recurrence are still unlikely to be cured. Carefully planned and meticulously executed surgery, appropriate adjuvant chemotherapy and radiotherapy still play major roles in treatment, and they can significantly increase cure rates, especially in the advanced stages. This book contains a wealth of the latest international data and detailed information assist professionals in making the best possible decisions regarding specific and patient-oriented treatments. From the general introduction to the principles of adjuvant chemotherapy in chapter one to all the details in the chapters covering specific cancers, we hope this book will inspire veterans in the field with new ideas and help to guide and educate young doctors and researchers, all towards the ultimate goal of providing better care for our patients.
Publisher:
ISBN: 9781536139334
Category : Chemotherapy
Languages : en
Pages : 0
Book Description
In the age of constant knowledge via computer accessibility, the effort to write a book on adjuvant chemotherapy may seem almost futile. However, the information seen online is usually fragmented, without context, and often somewhat unreliable. This book aims to provide a handy and reliable reference to better understand both the current situation and the future directions in the field of adjuvant chemotherapy. Its ten chapters covering major cancers were written by prominent researchers with decades of experience in clinical settings as well as in related fields of research. Owing mostly to the development of novel cancer drugs, cytotoxic agents, targeting agents and immune check point inhibitors, the prognosis of all cancers has markedly improved. On the other hand, determining the best way to use these drugs is becoming more and more complicated, and most patients after recurrence are still unlikely to be cured. Carefully planned and meticulously executed surgery, appropriate adjuvant chemotherapy and radiotherapy still play major roles in treatment, and they can significantly increase cure rates, especially in the advanced stages. This book contains a wealth of the latest international data and detailed information assist professionals in making the best possible decisions regarding specific and patient-oriented treatments. From the general introduction to the principles of adjuvant chemotherapy in chapter one to all the details in the chapters covering specific cancers, we hope this book will inspire veterans in the field with new ideas and help to guide and educate young doctors and researchers, all towards the ultimate goal of providing better care for our patients.
Breast Cancer in Young Women
Author: Oreste Gentilini
Publisher: Springer Nature
ISBN: 3030247627
Category : Medical
Languages : en
Pages : 218
Book Description
This contributed book covers all aspects concerning the clinical scenario of breast cancer in young women, providing physicians with the latest information on the topic. Young women are a special subset of patients whose care requires dedicated expertise. The book, written and edited by internationally recognized experts who have been directly involved in the international consensus guidelines for breast cancer in young women, pays particular attention to how the disease and its planned treatment can be effectively communicated to young patients. Highly informative and carefully structured, it provides both theoretical and practice-oriented insight for practitioners and professionals involved in the different phases of treatment, from diagnosis to intervention, to follow-up – without neglecting the important role played by prevention.
Publisher: Springer Nature
ISBN: 3030247627
Category : Medical
Languages : en
Pages : 218
Book Description
This contributed book covers all aspects concerning the clinical scenario of breast cancer in young women, providing physicians with the latest information on the topic. Young women are a special subset of patients whose care requires dedicated expertise. The book, written and edited by internationally recognized experts who have been directly involved in the international consensus guidelines for breast cancer in young women, pays particular attention to how the disease and its planned treatment can be effectively communicated to young patients. Highly informative and carefully structured, it provides both theoretical and practice-oriented insight for practitioners and professionals involved in the different phases of treatment, from diagnosis to intervention, to follow-up – without neglecting the important role played by prevention.
TNM Atlas
Author: Christian Wittekind
Publisher: John Wiley & Sons
ISBN: 1118695607
Category : Medical
Languages : en
Pages : 739
Book Description
The complete, authoritative TNM cancer classification and staging system—now illustrated with new, full-colour figures for fast, effective, anatomical referencing Referring to “Tumour,” “Node,” and “Metastasis,” the TNM system is the most widely used means for classifying and staging the extent of cancer spread. Published in affiliation with the Union for International Cancer Control (UICC), TNM Atlas, Sixth Edition presents the illustrated version of the TNM Classification of Malignant Tumours, Seventh Edition, promoting the uniform application of the TNM classification in cancer practice. Utilizing beautiful, full-colour medical artwork—illustrating the T and N categories in clear, easily understood graphics—this book aides in the practical application of the TNM classification system. It enables all disciplines involved in cancer classification, staging, and treatment to reach a more standardized understanding and documentation of the anatomical spread of tumours, and further enhances the dissemination and use of the TNM classification. The TNM Atlas, Sixth Edition: • Is based upon the very latest TNM Classification data available in TNM Classification of Malignant Tumours, Seventh Edition • Features over 500 full-colour figures that clearly illustrate and highlight anatomical sites of cancer involvement • Makes TNM classification even more clinically applicable in the day-to-day environment • Is an extremely useful tool for clinical reference, teaching, discussion, and patient education Based in Geneva, the UICC is one of the most widely affiliated cancer organisations in the world, with its core mission being cancer classification and control. Its TNM Atlas, Sixth Edition is a valuable reference for all medical, surgical, and radiation oncologists, anatomical and surgical pathologists, cancer registrars, oncology nurses and physician extenders, international cancer care centres, and governmental and NGOs dedicated to cancer control. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play.
Publisher: John Wiley & Sons
ISBN: 1118695607
Category : Medical
Languages : en
Pages : 739
Book Description
The complete, authoritative TNM cancer classification and staging system—now illustrated with new, full-colour figures for fast, effective, anatomical referencing Referring to “Tumour,” “Node,” and “Metastasis,” the TNM system is the most widely used means for classifying and staging the extent of cancer spread. Published in affiliation with the Union for International Cancer Control (UICC), TNM Atlas, Sixth Edition presents the illustrated version of the TNM Classification of Malignant Tumours, Seventh Edition, promoting the uniform application of the TNM classification in cancer practice. Utilizing beautiful, full-colour medical artwork—illustrating the T and N categories in clear, easily understood graphics—this book aides in the practical application of the TNM classification system. It enables all disciplines involved in cancer classification, staging, and treatment to reach a more standardized understanding and documentation of the anatomical spread of tumours, and further enhances the dissemination and use of the TNM classification. The TNM Atlas, Sixth Edition: • Is based upon the very latest TNM Classification data available in TNM Classification of Malignant Tumours, Seventh Edition • Features over 500 full-colour figures that clearly illustrate and highlight anatomical sites of cancer involvement • Makes TNM classification even more clinically applicable in the day-to-day environment • Is an extremely useful tool for clinical reference, teaching, discussion, and patient education Based in Geneva, the UICC is one of the most widely affiliated cancer organisations in the world, with its core mission being cancer classification and control. Its TNM Atlas, Sixth Edition is a valuable reference for all medical, surgical, and radiation oncologists, anatomical and surgical pathologists, cancer registrars, oncology nurses and physician extenders, international cancer care centres, and governmental and NGOs dedicated to cancer control. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play.
Pediatric Oncology 1
Author: G. Bennett Humphrey
Publisher: Springer Science & Business Media
ISBN: 9400982194
Category : Medical
Languages : en
Pages : 302
Book Description
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre quently publish good indepth reviews of cancer topics, and published sympo sium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the Specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Publisher: Springer Science & Business Media
ISBN: 9400982194
Category : Medical
Languages : en
Pages : 302
Book Description
Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general onco logy textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals fre quently publish good indepth reviews of cancer topics, and published sympo sium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by divid ing the oncology literature into specific subdivisions such as lung cancer, genitourinary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the Specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Adjuvant Therapy of Breast Cancer
Author: I. Craig Henderson
Publisher:
ISBN: 9781461534976
Category :
Languages : en
Pages : 484
Book Description
Publisher:
ISBN: 9781461534976
Category :
Languages : en
Pages : 484
Book Description
Foundations of Colorectal Cancer
Author: Alejandro Pazos Sierra
Publisher: Elsevier
ISBN: 0323900550
Category : Medical
Languages : en
Pages : 670
Book Description
Foundations of Colorectal Cancer provides a holistic and comprehensive dive into colorectal cancer, discussing the contributions of each discipline that studies it, allowing its understanding from the most demographic and ethical facts, to the treatment process, its varieties and genetic background. Written by experts in diverse areas such as cancer research, oncology, genetics, biochemistry, psychology, social sciences, bioinformatics and palliative care, the book brings real-world experiences to help readers with any challenge they may face when dealing with patients or during their research workflow. The content is split into nine sections: Clinical manifestations and disease detection, covering primary and secondary prevention, and the role of primary care; Diagnosis and staging, discussing endoscopy, colonoscopy, molecular pathology, and anatomopathological diagnosis; Treatment, including endoscopic, surgical, radiological, and postoperative approaches; Molecular and biological mechanisms, with the role of intestinal microbiota, stem cells and signaling pathways; New diagnostic methods, encompassing biomarkers and bioinformatics tools for research; Biobanks, with an overview of their regulations and importance in the research; Epidemiological studies, focusing on incidence and mortality globally and by regions; Hereditary colorectal cancer, differentiating nonpolyposis and polyposis types; and Addressing the consequences of colorectal cancer, covering psychological effects, nutrition and ethical issues. Provides a multidisciplinary approach with a holistic view of colorectal cancer, ranging from basic science to population studies, with its social and environmental influences and impacts, interpreting the disease as a medical, chemical, physical, microbial, psychological, and social condition Written by a diverse group of specialists with complementary expertise, including oncologists, radiologists, biochemists, surgeons, psychologists, social workers and clinicians, all members of the Galician Research Network of Colorectal Cancer (REGICC) with vast collaboration experience to bring comprehensive knowledge on the subject Encompasses reliable information suitable for different workers within the healthcare sector and research community dedicated to colorectal cancer, from clinicians and healthcare providers, researchers on several aspects of cancer, to bioinformaticians who deal with health data Includes many case studies throughout the chapters discussed by specialists with high scientific accuracy and didactic value, in order to clearly and precisely share their professional experience on the subject with readers
Publisher: Elsevier
ISBN: 0323900550
Category : Medical
Languages : en
Pages : 670
Book Description
Foundations of Colorectal Cancer provides a holistic and comprehensive dive into colorectal cancer, discussing the contributions of each discipline that studies it, allowing its understanding from the most demographic and ethical facts, to the treatment process, its varieties and genetic background. Written by experts in diverse areas such as cancer research, oncology, genetics, biochemistry, psychology, social sciences, bioinformatics and palliative care, the book brings real-world experiences to help readers with any challenge they may face when dealing with patients or during their research workflow. The content is split into nine sections: Clinical manifestations and disease detection, covering primary and secondary prevention, and the role of primary care; Diagnosis and staging, discussing endoscopy, colonoscopy, molecular pathology, and anatomopathological diagnosis; Treatment, including endoscopic, surgical, radiological, and postoperative approaches; Molecular and biological mechanisms, with the role of intestinal microbiota, stem cells and signaling pathways; New diagnostic methods, encompassing biomarkers and bioinformatics tools for research; Biobanks, with an overview of their regulations and importance in the research; Epidemiological studies, focusing on incidence and mortality globally and by regions; Hereditary colorectal cancer, differentiating nonpolyposis and polyposis types; and Addressing the consequences of colorectal cancer, covering psychological effects, nutrition and ethical issues. Provides a multidisciplinary approach with a holistic view of colorectal cancer, ranging from basic science to population studies, with its social and environmental influences and impacts, interpreting the disease as a medical, chemical, physical, microbial, psychological, and social condition Written by a diverse group of specialists with complementary expertise, including oncologists, radiologists, biochemists, surgeons, psychologists, social workers and clinicians, all members of the Galician Research Network of Colorectal Cancer (REGICC) with vast collaboration experience to bring comprehensive knowledge on the subject Encompasses reliable information suitable for different workers within the healthcare sector and research community dedicated to colorectal cancer, from clinicians and healthcare providers, researchers on several aspects of cancer, to bioinformaticians who deal with health data Includes many case studies throughout the chapters discussed by specialists with high scientific accuracy and didactic value, in order to clearly and precisely share their professional experience on the subject with readers
Preoperative (Neoadjuvant) Chemotherapy
Author: Joseph Ragaz
Publisher: Springer Science & Business Media
ISBN: 3642826717
Category : Medical
Languages : en
Pages : 172
Book Description
Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.
Publisher: Springer Science & Business Media
ISBN: 3642826717
Category : Medical
Languages : en
Pages : 172
Book Description
Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.