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Author: Maurice N Collins
Publisher: Smithers Rapra
ISBN: 1909030783
Category : Medical
Languages : en
Pages : 238
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Book Description
Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. Its properties, both physical and biochemical, in solution or hydrogel form, are extremely attractive for various technologies concerned with body repair. This book considers the materials science behind some of the important biomedical and therapeutic applications that are emerging for HA. Key characteristics such as its mechanical properties, biological function and degradation are discussed. The latest technologies in chemical modification and crosslinking strategies are analysed and emerging applications in soft and hard tissue repair are highlighted. The first objective of the book, which consists of a collection of chapters from leading researchers across the globe, is to highlight the role of HA based hydrogels as scaffolds in sustaining stem cells for transplantation and regrowth. The second objective is to detail the significant influence of HA derived materials in the latest advances in cancer therapy, general therapeutics and cosmetics. The third objective is to link the structure-property relationships of HA to medical function and application while reflecting on current clinical and market trends. The book will be of interest to those involved in HA research for medical device and therapeutic applications. Graduate and undergraduate students engaged in the fields of biomedical engineering, materials science, chemistry, medical science, pharmaceutical science and polymer science will find this book of particular interest.
Author: V. N. Khabarov
Publisher: John Wiley & Sons
ISBN: 1118633792
Category : Science
Languages : en
Pages : 228
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Book Description
Hyaluronic acid is an essential part of connective, epithelial and neural tissues, and contributes to cell proliferation and migration. It is used as a stimulating agent for collagen synthesis and is a common ingredient in skin-care products, a multi-billion dollar industry, as it is believed to be a key factor in fighting the aging process. Hyaluronic Acid: Production, Properties, Application in Biology and Medicine consists of six chapters discussing the various issues of hyaluronic acid research. In Chapter 1, a historical analysis recounts the discovery and milestones of the research leading to the practical applications of hyaluronan. Chapter 2 is dedicated to biological role of the hyaluronic acid in nature, in particular in the human body. The chapter starts from the phylogenesis of hyaluronic acid, then describes hyaluronan functions in human ontogenesis and especially the role which hyaluronan plays in extracellular matrix of the different tissues. Chapter 3 describes the methods to manufacture and purify hyaluronic acid, including the analytical means for assessing quality of the finished product. Chapter 4 discusses the structure and rheological properties of hyaluronic acid considering effects on conformation and biological properties related to molecular weight. In Chapter 5, the physical and chemical methods for modifying the structure of hyaluronan are discussed including cross-linking using bi-functional reagents, solid-phase modification and effects of the combined action of high pressures and shift deformation. The final chapter focuses on the products derived from hyaluronic acid, including therapeutics composed of modified hyaluronan conjugated to vitamins, amino acids and oligo-peptides. The biological roles and medical applications of this polysaccharide have been extensively studied and this book provides a wealth of scientific data demonstrating the critical role of hyaluronic acid and its promise as a multifaceted bio-macromolecule. Approaching hyaluronic acid from multiple angles, this book links relationships between its biological functions, structure and physical–chemical properties. It will be an invaluable resource to researchers, both industrial and academic, involved in all aspects of hyaluronan-based technologies.
Author: Maurice N Collins
Publisher: Smithers Rapra
ISBN: 1909030783
Category : Medical
Languages : en
Pages : 238
Get Book Here
Book Description
Hyaluronic acid (HA) is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterials science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. Its properties, both physical and biochemical, in solution or hydrogel form, are extremely attractive for various technologies concerned with body repair. This book considers the materials science behind some of the important biomedical and therapeutic applications that are emerging for HA. Key characteristics such as its mechanical properties, biological function and degradation are discussed. The latest technologies in chemical modification and crosslinking strategies are analysed and emerging applications in soft and hard tissue repair are highlighted. The first objective of the book, which consists of a collection of chapters from leading researchers across the globe, is to highlight the role of HA based hydrogels as scaffolds in sustaining stem cells for transplantation and regrowth. The second objective is to detail the significant influence of HA derived materials in the latest advances in cancer therapy, general therapeutics and cosmetics. The third objective is to link the structure-property relationships of HA to medical function and application while reflecting on current clinical and market trends. The book will be of interest to those involved in HA research for medical device and therapeutic applications. Graduate and undergraduate students engaged in the fields of biomedical engineering, materials science, chemistry, medical science, pharmaceutical science and polymer science will find this book of particular interest.
Author: Robert E. Brooks
Publisher:
ISBN:
Category : Hyaluronic acid
Languages : en
Pages : 20
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Book Description
Author: Hélène Barbier du Vimont
Publisher: Médicis
ISBN: 9782853274692
Category :
Languages : fr
Pages : 91
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Book Description
L'acide hyaluronique est présent dans le corps partout où il y a des tissus souples et élastiques, les cartilages et surtout la peau. Cette dernière lui doit sa souplesse, sa jeunesse, son élasticité et son absence de rides ! Abus de soleil, années qui passent, parfois problèmes de santé contrarient les apports d'acide hyaluronique à la peau. Ridules, rides et affaissement des tissus menacent. On peut envisager les injections, bien sûr, mais leur coût et la courte durée de leurs effets peuvent vous décourager. D'autant qu'il y a tellement plus simple ! La complémentation, qui permet d'apporter à votre peau ce précieux nutriment et qui, en prime, sera bénéfique à vos articulations. Découvrez ce qu'est exactement l'acide hyaluronique, pourquoi il contribue à maintenir la souplesse et la texture de votre peau et comment vous complémenter pour redonner à votre peau toute son intégralité et toute sa jeunesse.
Author: Melvin D. Schoenberg
Publisher:
ISBN:
Category : Hyaluronic acid
Languages : en
Pages : 20
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Book Description
Author: J.W. Kuo
Publisher: CRC Press
ISBN: 1420037641
Category : Medical
Languages : en
Pages : 238
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Book Description
The ballooning body of research devoted to hyaluronan (HA) reflects its enormous potential for various medical applications. There have been many successes of varying degrees in the development of medical products based on HA, but also some setbacks. While there is obviously ample information available on the chemistry and various properties of thi
Author: Hari G. Garg
Publisher: Elsevier
ISBN: 0080472222
Category : Science
Languages : en
Pages : 625
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Book Description
It was probably the French chemist Portes, who first reported in 1880 that the mucin in the vitreous body, which he named hyalomucine, behaved differently from other mucoids in cornea and cartilage. Fifty four years later Karl Meyer isolated a new polysaccharide from the vitreous, which he named hyaluronic acid. Today its official name is hyaluronan, and modern-day research on this polysaccharide continues to grow. Expertly written by leading scientists in the field, this book provides readers with a broad, yet detailed review of the chemistry of hyaluronan, and the role it plays in human biology and pathology. Twenty-seven chapters present a sequence leading from the chemistry and biochemistry of hyaluronan, followed by its role in various pathological conditions, to modified hylauronans as potential therapeutic agents and finally to the functional, structural and biological properties of hyaluronidases. Chemistry and Biology of Hyaluronan covers the many interesting facets of this fascinating molecule, and all chapters are intended to reach the wider research community. - Comprehensive look at the chemistry and biology of hyaluronans - Essential to Chemists, Biochemists and Medical researchers - Broad yet detailed review of this rapidly growing research area
Author: Riia Rautiola
Publisher:
ISBN: 9781536170603
Category : Science
Languages : en
Pages : 152
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Book Description
"Hyaluronic acid, or hyaluronan, is a water soluble, anionic extracellular matrix glycosaminoglycan polymer with variable molecular weight that determines its physiological role, rheological properties and applications. Since its discovery in the early 1930s, there has been an increased awareness concerning the biology of hyaluronic acid, its signaling pathways and its role in the biomedical and cosmeceutical industry. Being an endogenous molecule, hyaluronic acid is biocompatible, biodegradable, and has strong mucoadhesive, viscoelastic properties. The authors provide chemical modification approaches to hyaluronic acid, as well as address the magnitude of applications of hyaluronic acid-based targeted drug vectors and patents. The closing study discusses glycosaminoglycans, a specialized group of unbranched, anionic disaccharide polymers attached by a covalent linkage to the membrane proteins via sulphate groups in their sugar moieties"--
Author: Alberto Passi
Publisher: Springer Nature
ISBN: 3031303008
Category : Science
Languages : en
Pages : 220
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Book Description
This book addresses the structural and biological properties of the extracellular matrix component and glycosaminoglycan polymer hyaluronan (or hyaluronic acid, HA). The book discusses various aspects of HA biology, e.g., HA synthesis and degradation, as well as the role of HA in embryogenesis, development, and cell maintenance. The reader will learn about the role of HA in different tissues as well as its biological activities triggered by the interaction with different HA receptors. A closer look is had at the involvement of HA in human pathologies such as cancer, kidney fibrosis and wound healing. Biotechnological and biomedical applications for HA such as scaffold generation and drug delivery, including the novel synthetic sulphated HA are explored. This work will appeal to a wide readership within the extracellular matrix and hyaluronan field. It can serve as an introduction to the field for junior scientists but can also help senior scientists to gain a broader view of the field beyond their area of specialization. The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology and the International Society for Matrix Biology.
Author: Iza Aissaoui
Publisher:
ISBN:
Category :
Languages : fr
Pages : 0
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Book Description
Le secteur de la médecine/chirurgie esthétique connait un essor considérable, et tout spécialement depuis la découverte de l'acide hyaluronique injectable (AHI). En effet, les deux dernières décennies, le concept de beauté et d'image sociale est devenue un besoin et une demande en soin esthétique. La réponse, médicale ou informelle, est devenue avec le temps un enjeu juridique (au regard des fake injectors) et sanitaire (au regard des complications relevées), auquel il fallait adapter le cadre législatif et règlementaire. Pour ce faire, • D'une part, et pour vérifier et affirmer les bienfaits d'un tel acte médical, nous avons développé les connaissances fondamentales actualisées, en biologie cutanée et en biochimie de l'AHI, dévoilé les processus industriels et règlementaires du dispositif médical AHI et analysé l'approche thérapeutique avec ses effets indésirables en médecine esthétique ; • D'autre part, nous avons abordé la problématique de l'acte en secteur informel. En termes d'enjeu de santé publique, nous avons présenté et salué la récente réaction des pouvoirs publics qui a fait évoluer la législation et les règlementations, et ce à tous les niveaux de ce secteur, et nous nous sommes permis d'avancer des préconisations et d'ouvrir des débats en vue d'une évolution supplémentaire des dispositifs réglementaires.
