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Author: Olli Mali
Publisher: Springer Science & Business Media
ISBN: 9400775814
Category : Computers
Languages : en
Pages : 366
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Book Description
The importance of accuracy verification methods was understood at the very beginning of the development of numerical analysis. Recent decades have seen a rapid growth of results related to adaptive numerical methods and a posteriori estimates. However, in this important area there often exists a noticeable gap between mathematicians creating the theory and researchers developing applied algorithms that could be used in engineering and scientific computations for guaranteed and efficient error control. The goals of the book are to (1) give a transparent explanation of the underlying mathematical theory in a style accessible not only to advanced numerical analysts but also to engineers and students; (2) present detailed step-by-step algorithms that follow from a theory; (3) discuss their advantages and drawbacks, areas of applicability, give recommendations and examples.
Author: Olli Mali
Publisher: Springer Science & Business Media
ISBN: 9400775814
Category : Computers
Languages : en
Pages : 366
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Book Description
The importance of accuracy verification methods was understood at the very beginning of the development of numerical analysis. Recent decades have seen a rapid growth of results related to adaptive numerical methods and a posteriori estimates. However, in this important area there often exists a noticeable gap between mathematicians creating the theory and researchers developing applied algorithms that could be used in engineering and scientific computations for guaranteed and efficient error control. The goals of the book are to (1) give a transparent explanation of the underlying mathematical theory in a style accessible not only to advanced numerical analysts but also to engineers and students; (2) present detailed step-by-step algorithms that follow from a theory; (3) discuss their advantages and drawbacks, areas of applicability, give recommendations and examples.
Author: Mark Stauffer
Publisher: BoD – Books on Demand
ISBN: 1789230845
Category : Science
Languages : en
Pages : 176
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Book Description
This book seeks to introduce the reader to current methodologies in analytical calibration and validation. This collection of contributed research articles and reviews addresses current developments in the calibration of analytical methods and techniques and their subsequent validation. Section 1, "Introduction," contains the Introductory Chapter, a broad overview of analytical calibration and validation, and a brief synopsis of the following chapters. Section 2 "Calibration Approaches" presents five chapters covering calibration schemes for some modern analytical methods and techniques. The last chapter in this section provides a segue into Section 3, "Validation Approaches," which contains two chapters on validation procedures and parameters. This book is a valuable source of scientific information for anyone interested in analytical calibration and validation.
Author: Chung Chow Chan
Publisher: John Wiley & Sons
ISBN: 1118060318
Category : Science
Languages : en
Pages : 363
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Book Description
Practical approaches to ensure that analytical methods and instruments meet GMP standards and requirements Complementing the authors' first book, Analytical Method Validation and Instrument Performance Verification, this new volume provides coverage of more advanced topics, focusing on additional and supplemental methods, instruments, and electronic systems that are used in pharmaceutical, biopharmaceutical, and clinical testing. Readers will gain new and valuable insights that enable them to avoid common pitfalls in order to seamlessly conduct analytical method validation as well as instrument operation qualification and performance verification. Part 1, Method Validation, begins with an overview of the book's risk-based approach to phase appropriate validation and instrument qualification; it then focuses on the strategies and requirements for early phase drug development, including validation of specific techniques and functions such as process analytical technology, cleaning validation, and validation of laboratory information management systems Part 2, Instrument Performance Verification, explores the underlying principles and techniques for verifying instrument performance—coverage includes analytical instruments that are increasingly important to the pharmaceutical industry, such as NIR spectrometers and particle size analyzers—and offers readers a variety of alternative approaches for the successful verification of instrument performance based on the needs of their labs At the end of each chapter, the authors examine important practical problems and share their solutions. All the methods covered in this book follow Good Analytical Practices (GAP) to ensure that reliable data are generated in compliance with current Good Manufacturing Practices (cGMP). Analysts, scientists, engineers, technologists, and technical managers should turn to this book to ensure that analytical methods and instruments are accurate and meet GMP standards and requirements.
Author: Chung Chow Chan
Publisher: John Wiley & Sons
ISBN: 047146371X
Category : Science
Languages : en
Pages : 320
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Book Description
Validation describes the procedures used to analyze pharmaceutical products so that the data generated will comply with the requirements of regulatory bodies of the US, Canada, Europe and Japan. Calibration of Instruments describes the process of fixing, checking or correcting the graduations of instruments so that they comply with those regulatory bodies. This book provides a thorough explanation of both the fundamental and practical aspects of biopharmaceutical and bioanalytical methods validation. It teaches the proper procedures for using the tools and analysis methods in a regulated lab setting. Readers will learn the appropriate procedures for calibration of laboratory instrumentation and validation of analytical methods of analysis. These procedures must be executed properly in all regulated laboratories, including pharmaceutical and biopharmaceutical laboratories, clinical testing laboratories (hospitals, medical offices) and in food and cosmetic testing laboratories.
Author: Tadeusz Chrobak
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Author: James O. Westgard
Publisher: AACC Press
ISBN: 9781886958197
Category : Business & Economics
Languages : en
Pages : 292
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Book Description
With the publication of the Final CLIA Rule, new method validation responsibilities came to the laboratory. Previously, moderately complex methods did not need to be validated. But the Final Rule combined moderately and highly complex methods into a category of non-waived methods. Now Laboratories must validate all non-waived methods introduced after April 24, 2003. To help laboratory professionals comply with these new regulatory changes, a second edition of this manual was prepared. Book jacket.
Author: Dolores R. Wallace
Publisher: DIANE Publishing
ISBN: 0788143409
Category : Computer software
Languages : en
Pages : 97
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Book Description
Computing systems are employed in the health care environment in efforts to increase reliability of care and reduce costs. Software verification and validation (V&V) is an aid in determining that the software requirements are implemented correctly and completely and are traceable to system requirements. It helps to ensure that those system functions controlled by software are secure, reliable, and maintainable. Software V&V is conducted throughout the planning, development and maintenance of software systems, including knowledge based systems, and may assist in assuring appropriate reuse of software.
Author: Craig Silverman
Publisher: Union Square + ORM
ISBN: 1402774494
Category : Language Arts & Disciplines
Languages : en
Pages : 236
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Book Description
This look at careless journalism—from hilarious mistakes to egregious ethical lapses—is “chock-full of amusing historical anecdotes” (Publishers Weekly). Winner of the National Press Club’s Arthur Rowse Award for Press Criticism We regret the error: it’s a phrase that appears in newspapers almost daily, the standard notice that something went terribly wrong in the reporting, editing, or printing of an article. From Craig Silverman, the proprietor of www.RegretTheError.com, one of the Internet’s most popular media-related websites, comes a collection of funny, shocking, and sometimes disturbing journalistic slip-ups and corrections. On display are all types of media inaccuracy—from typos to “fuzzy math” to “obiticide” (printing the obituary of a person very much alive and well) to complete and utter ethical lapses. While some of the errors can be laugh-out-loud funny, the book also serves as a sobering journey through the history of media mistakes (including the outrageous hoaxes that dominated newspapers during the circulation wars of the nineteenth century) and a serious muckraking investigation of contemporary journalism’s lack of accountability to the public. Regret the Error shines a spotlight on the media’s carelessness and the sometimes tragic and calamitous consequences of weak or non-existent fact checking. “Mixing humorous corrections taken from large and small newspapers alike, Silverman gives historical context to the current problems . . . and then proposes solutions for busy newsrooms.” —Variety
Author: Dalkir, Kimiz
Publisher: IGI Global
ISBN: 1799825450
Category : Language Arts & Disciplines
Languages : en
Pages : 375
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Book Description
In the current day and age, objective facts have less influence on opinions and decisions than personal emotions and beliefs. Many individuals rely on their social networks to gather information thanks to social media’s ability to share information rapidly and over a much greater geographic range. However, this creates an overall false balance as people tend to seek out information that is compatible with their existing views and values. They deliberately seek out “facts” and data that specifically support their conclusions and classify any information that contradicts their beliefs as “false news.” Navigating Fake News, Alternative Facts, and Misinformation in a Post-Truth World is a collection of innovative research on human and automated methods to deter the spread of misinformation online, such as legal or policy changes, information literacy workshops, and algorithms that can detect fake news dissemination patterns in social media. While highlighting topics including source credibility, share culture, and media literacy, this book is ideally designed for social media managers, technology and software developers, IT specialists, educators, columnists, writers, editors, journalists, broadcasters, newscasters, researchers, policymakers, and students.
Author: William L. Oberkampf
Publisher: Cambridge University Press
ISBN: 1139491768
Category : Computers
Languages : en
Pages : 782
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Book Description
Advances in scientific computing have made modelling and simulation an important part of the decision-making process in engineering, science, and public policy. This book provides a comprehensive and systematic development of the basic concepts, principles, and procedures for verification and validation of models and simulations. The emphasis is placed on models that are described by partial differential and integral equations and the simulations that result from their numerical solution. The methods described can be applied to a wide range of technical fields, from the physical sciences, engineering and technology and industry, through to environmental regulations and safety, product and plant safety, financial investing, and governmental regulations. This book will be genuinely welcomed by researchers, practitioners, and decision makers in a broad range of fields, who seek to improve the credibility and reliability of simulation results. It will also be appropriate either for university courses or for independent study.
