A New Generation of Polymer Nanoparticles for Drug Delivery PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download A New Generation of Polymer Nanoparticles for Drug Delivery PDF full book. Access full book title A New Generation of Polymer Nanoparticles for Drug Delivery by Cédric Chauvierre. Download full books in PDF and EPUB format.
Author: Cédric Chauvierre
Publisher: Editions Universitaires Europeennes
ISBN: 9786131535178
Category : Drug carriers (Pharmacy)
Languages : en
Pages : 296
Get Book Here
Book Description
One of the main interest of using polymer nanoparticles as drug carrier systems is to control the delivery of the drug and of their biodistribution. It was clearly demonstrated that surface properties of nanoparticles were the key factor which determined the in vivo fate of such a cerrier. While a neutral (stealth(r)) system of appropriate circulation lifetime as poly(ethylene glycol) chains coated nanoparticles is already of interest, an additional positive function can be feasible by a proper design of the exposed nanoparticle surface by using polysaccharide chains which are involved in tissue addressing. In this thesis, monodisperse biodegradable nanoparticles were developed from an original redox radical polymerization reaction of alkylcyanoacrylates in emulsion and requiring only one step in aqueous media. The nanoparticle surfaces exhibited polysaccharides that maintain their biological properties. The nanoparticles were very stable, and their characteristics can be modulated. This offers a new strategy for the design of modular biomimetic nanoparticles as drug carrier systems with multiple functions, with applications such as blood substitutes.
Author: Cédric Chauvierre
Publisher: Editions Universitaires Europeennes
ISBN: 9786131535178
Category : Drug carriers (Pharmacy)
Languages : en
Pages : 296
Get Book Here
Book Description
One of the main interest of using polymer nanoparticles as drug carrier systems is to control the delivery of the drug and of their biodistribution. It was clearly demonstrated that surface properties of nanoparticles were the key factor which determined the in vivo fate of such a cerrier. While a neutral (stealth(r)) system of appropriate circulation lifetime as poly(ethylene glycol) chains coated nanoparticles is already of interest, an additional positive function can be feasible by a proper design of the exposed nanoparticle surface by using polysaccharide chains which are involved in tissue addressing. In this thesis, monodisperse biodegradable nanoparticles were developed from an original redox radical polymerization reaction of alkylcyanoacrylates in emulsion and requiring only one step in aqueous media. The nanoparticle surfaces exhibited polysaccharides that maintain their biological properties. The nanoparticles were very stable, and their characteristics can be modulated. This offers a new strategy for the design of modular biomimetic nanoparticles as drug carrier systems with multiple functions, with applications such as blood substitutes.
Author: Ijeoma F. Uchegbu
Publisher: CRC Press
ISBN: 1000611248
Category : Medical
Languages : en
Pages : 426
Get Book Here
Book Description
Together, the nano explosion and the genomic revolution are ushering in a new frontier in drug delivery. In recent years we've seen how polymers can play a crucial role in controlling the rate of drug release, enhancing solubility and uptake, and limiting degradation and toxicity. In the very near future, they may well be used to deliver gene thera
Author: Ali Demir Sezer
Publisher: BoD – Books on Demand
ISBN: 9535122479
Category : Medical
Languages : en
Pages : 400
Get Book Here
Book Description
This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.
Author: Christine Vauthier
Publisher: Springer
ISBN: 3319414216
Category : Medical
Languages : en
Pages : 649
Get Book Here
Book Description
This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.
Author: José A. Pomposo
Publisher: John Wiley & Sons
ISBN: 3527806393
Category : Technology & Engineering
Languages : en
Pages : 504
Get Book Here
Book Description
This first book on this important and emerging topic presents an overview of the very latest results obtained in single-chain polymer nanoparticles obtained by folding synthetic single polymer chains, painting a complete picture from synthesis via characterization to everyday applications. The initial chapters describe the synthetics methods as well as the molecular simulation of these nanoparticles, while subsequent chapters discuss the analytical techniques that are applied to characterize them, including size and structural characterization as well as scattering techniques. The final chapters are then devoted to the practical applications in nanomedicine, sensing, catalysis and several other uses, concluding with a look at the future for such nanoparticles. Essential reading for polymer and materials scientists, materials engineers, biochemists as well as environmental chemists.
Author: Yashwant V Pathak
Publisher: Springer
ISBN: 3030061159
Category : Medical
Languages : en
Pages : 499
Get Book Here
Book Description
This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.
Author: Devasier Bennet
Publisher:
ISBN:
Category : Science
Languages : en
Pages :
Get Book Here
Book Description
Polymer Nanoparticles for Smart Drug Delivery.
Author: Prashant Kesharwani
Publisher: Academic Press
ISBN: 0128173319
Category : Medical
Languages : en
Pages : 434
Get Book Here
Book Description
Polymeric Nanoparticles as Promising Tool for Anti-cancer Therapeutics provides an understanding of polymeric compounds and their use in cancer therapies. The book begins by giving an overview of the current status, future challenges and potential utilization of polymeric nanoparticles. It then covers specific polymeric nanoparticles through contributions from world-renowned experts and researchers. Chapters examine specific polymeric nanoparticles, their development as potential targeted delivery systems, and cancer characteristics that can be targeted for therapy development. The book synthesizes current research trends in the field, thus enhancing existing knowledge of nanomedicine, drug delivery and therapeutic intervention strategies in human cancers. Users will find this to be an ideal reference for research scientists and those in the pharmaceutical and medical fields who are working to develop novel cancer therapies using nanoparticle-based delivery systems. Explores the development of polymeric nanoparticle systems for the purpose of cancer therapy Presents thoroughly analyzed data and results regarding the usage of polymeric nanoparticles-based platforms for the diagnosis and treatment of cancer Highlights various cancer characteristics that can be targeted for therapeutic development using polymeric nanoparticles
Author: Rebecca A. Bader
Publisher: John Wiley & Sons
ISBN: 1118747801
Category : Social Science
Languages : en
Pages : 395
Get Book Here
Book Description
Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-specialists as well as a graduate level text for drug delivery courses.
Author: Saurabh Bhatia
Publisher: Springer
ISBN: 3319411292
Category : Technology & Engineering
Languages : en
Pages : 235
Get Book Here
Book Description
This book describes 200 bio-polymers, including the most recent and advanced nanotechnology applications. The applications of various bio-medical and other future potential uses are covered and examined in depth. Systematic discussion of current leading natural polymers is also included.
