A Guide to the Polyamines PDF Download
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Author: Seymour Stanley Cohen
Publisher: Oxford University Press, USA
ISBN:
Category : Science
Languages : en
Pages : 632
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Book Description
The polyamines are ubiquitous and essential organic cations in prokaryotic and eukaryotic cells. This book is a comprehensive survey of the development of knowledge of their physiological and structural roles. Currently, the genetic and regulatory determinants of the amines and their cellular composition are being explored actively as parameters of normal physiology and aberrant pathologies. Cancer, virus infection, and protozoan parasitism are major examples of the later groups. Studies of the control of polyamine metabolism are providing important therapeutic leads. Further, the structural roles of the amines are being determined at molecular levels, contributing to the understanding of polynucleotide and protein organization and interaction, as well as to the solution of problems of genome transfer. These subjects describe a burgeoning biochemical area involving compounds whose roles in cytoplasmic and nuclear function include numerous aspects of organelle structure, polymer synthesis, and interactions.
Author: Seymour Stanley Cohen
Publisher: Oxford University Press, USA
ISBN:
Category : Science
Languages : en
Pages : 632
Get Book Here
Book Description
The polyamines are ubiquitous and essential organic cations in prokaryotic and eukaryotic cells. This book is a comprehensive survey of the development of knowledge of their physiological and structural roles. Currently, the genetic and regulatory determinants of the amines and their cellular composition are being explored actively as parameters of normal physiology and aberrant pathologies. Cancer, virus infection, and protozoan parasitism are major examples of the later groups. Studies of the control of polyamine metabolism are providing important therapeutic leads. Further, the structural roles of the amines are being determined at molecular levels, contributing to the understanding of polynucleotide and protein organization and interaction, as well as to the solution of problems of genome transfer. These subjects describe a burgeoning biochemical area involving compounds whose roles in cytoplasmic and nuclear function include numerous aspects of organelle structure, polymer synthesis, and interactions.
Author: Michael T. McManus
Publisher: John Wiley & Sons
ISBN: 111822311X
Category : Science
Languages : en
Pages : 433
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Book Description
The plant hormone ethylene is one of the most important, being one of the first chemicals to be determined as a naturally-occurring growth regulator and influencer of plant development. It was also the first hormone for which significant evidence was found for the presence of receptors. This important new volume in Annual Plant Reviews is broadly divided into three parts. The first part covers the biosynthesis of ethylene and includes chapters on S-adenosylmethionine and the formation and fate of ACC in plant cells. The second part of the volume covers ethylene signaling, including the perception of ethylene by plant cells, CTR proteins, MAP kinases and EIN2 / EIN3. The final part covers the control by ethylene of cell function and development, including seed development, germination, plant growth, cell separation, fruit ripening, senescent processes, and plant-pathogen interactions. The Plant Hormone Ethylene is an extremely valuable addition to Wiley-Blackwell's Annual Plant Reviews. With contributions from many of the world's leading researchers in ethylene, and edited by Professor Michael McManus of Massey University, this volume will be of great use and interest to a wide range of plant scientists, biochemists and chemists. All universities and research establishments where plant sciences, biochemistry, chemistry, life sciences and agriculture are studied and taught should have access to this important volume.
Author: Taku Takahashi
Publisher:
ISBN: 9783039363193
Category :
Languages : en
Pages : 162
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Book Description
Polyamines are small organic compounds found in all living organisms. In recent years, there have been many exciting advances in our understanding of plant polyamines, such as the determination of the biosynthetic and catabolic pathways of plant polyamines and the identification of the roles that plant polyamines play in cellular processes. This Special Issue contains six original research papers and three review articles, providing valuable insights and information for future polyamine-related research.
Author: Taku Takahashi
Publisher: MDPI
ISBN: 3039363182
Category : Science
Languages : en
Pages : 162
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Book Description
Polyamines are small organic compounds found in all living organisms. In recent years, there have been many exciting advances in our understanding of plant polyamines, such as the determination of the biosynthetic and catabolic pathways of plant polyamines and the identification of the roles that plant polyamines play in cellular processes. This Special Issue contains six original research papers and three review articles, providing valuable insights and information for future polyamine-related research.
Author: Tomonobu Kusano
Publisher: Springer
ISBN: 443155212X
Category : Science
Languages : en
Pages : 324
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Book Description
This book covers key topics in polyamine research from a range of organisms, including plants, mammals, and prokaryotes such as bacteria and archaea. The book provides an introduction to general concepts in the field of polyamine research, as well as more detailed information. With the availability of genome sequence data from a broad range of organisms, the evolution of the genes involved in polyamine metabolism is discussed. The mode of action of polyamines has been shown to be dependent on cation channels, and this mechanism is described in the book. The origin of polyamine transporters (from bacteria, yeasts, and plants) is described. The various effects of polyamines on growth and survival are also documented. The book details the mechanisms of polyamine homeostasis and the role of polyamine molecules as precursors of secondary metabolites such as plant alkaloids and toxins derived from spiders and wasps. The role of polyamines in longevity and disease is discussed. A link between polyamine contents and cancer progression is reported, as is the use of polyamine metabolites as diagnostic markers in the initial stages of cancer. Moreover, a novel approach that utilizes the polyamine pathway of a parasite as a drug target in African sleeping sickness is described. Therefore, this book is a valuable resource, both as a textbook for undergraduate and graduate students and also as a reference book for front-line polyamine researchers.
Author: Roland W. Herzog
Publisher: World Scientific
ISBN: 9814280917
Category : Medical
Languages : en
Pages : 415
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Book Description
1. Non-viral gene therapy / Sean M. Sullivan -- 2. Adenoviral vectors / Stuart A. Nicklin and Andrew H. Baker -- 3. Retroviral vectors and integration analysis / Cynthia C. Bartholomae [und weitere] -- 4. Lentiviral vectors / Janka Matrai, Marinee K.L. Chuah and Thierry VandenDriessche -- 5. Herpes simplex virus vectors / William F. Goins [und weitere] -- 6. Adeno-Associated Viral (AAV) vectors / Nicholas Muzyczka -- 7. Regulatory RNA in gene therapy / Alfred. S. Lewin -- 8. DNA integrating vectors (Transposon, Integrase) / Lauren E. Woodard and Michele P. Calos -- 9. Homologous recombination and targeted gene modification for gene therapy / Matthew Porteus -- 10. Gene switches for pre-clinical studies in gene therapy / Caroline Le Guiner [und weitere] -- 11. Gene therapy for central nervous system disorders / Deborah Young and Patricia A. Lawlor -- 12. Gene therapy of hemoglobinopathies / Angela E. Rivers and Arun Srivastava -- 13. Gene therapy for primary immunodeficiencies / Aisha Sauer, Barbara Cassani and Alessandro Aiuti -- 14. Gene therapy for hemophilia / David Markusic, Babak Moghimi and Roland Herzog -- 15. Gene therapy for obesity and diabetes / Sergei Zolotukhin and Clive H. Wasserfall -- 16. Gene therapy for Duchenne muscular dystrophy / Takashi Okada and Shin'ichi Takeda -- 17. Cancer gene therapy / Kirsten A.K. Weigel-Van Aken -- 18. Gene therapy for autoimmune disorders / Daniel F. Gaddy, Melanie A. Ruffner and Paul D. Robbins -- 19. Gene therapy for inherited metabolic storage diseases / Cathryn Mah -- 20. Retinal diseases / Shannon E. Boye, Sanford L. Boye and William W. Hauswirth -- 21. A brief guide to gene therapy treatments for pulmonary diseases / Ashley T. Martino, Christian Mueller and Terence R. Flotte -- 22. Cardiovascular disease / Darin J. Falk, Cathryn S. Mah and Barry J. Byrne
Author: Alexander Vologodskii
Publisher: Cambridge University Press
ISBN: 1107034930
Category : Science
Languages : en
Pages : 279
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Book Description
This book surveys the last sixty years of research in the rapidly advancing field of DNA biophysics, addressing key questions and facilitating further research.
Author: Jian-Ying Wang
Publisher: Springer Science & Business Media
ISBN: 1597451452
Category : Science
Languages : en
Pages : 486
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Book Description
Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und- standing the molecular functions of cellular polyamines. These significant findings provide a fundamental basis to not only define the exact role of polyamines in physiology, but also to develop new therapeutic approaches for cancers and other diseases. The major objective of this book is to provide a timely and long lasting guide for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. It will provide a foundation based on research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research is divided into four main parts: Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell–Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to cellular and molecular functions of polyamines, but also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting of polyamines and polyamine metabolism. These points are addressed by int- nationally recognized experts in their contributions to this book.
Author: Aryadeep Roychoudhury
Publisher: John Wiley & Sons
ISBN: 1119551641
Category : Science
Languages : en
Pages : 702
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Book Description
A guide to the chemical agents that protect plants from various environmental stressors Protective Chemical Agents in the Amelioration of Plant Abiotic Stress offers a guide to the diverse chemical agents that have the potential to mitigate different forms of abiotic stresses in plants. Edited by two experts on the topic, the book explores the role of novel chemicals and shows how using such unique chemical agents can tackle the oxidative damages caused by environmental stresses. Exogenous application of different chemical agents or chemical priming of seeds presents opportunities for crop stress management. The use of chemical compounds as protective agents has been found to improve plant tolerance significantly in various crop and non-crop species against a range of different individually applied abiotic stresses by regulating the endogenous levels of the protective agents within plants. This important book: Explores the efficacy of various chemical agents to eliminate abiotic stress Offers a groundbreaking look at the topic and reviews the most recent advances in the field Includes information from noted authorities on the subject Promises to benefit agriculture under stress conditions at the ground level Written for researchers, academicians, and scientists, Protective Chemical Agents in the Amelioration of Plant Abiotic Stress details the wide range of protective chemical agents, their applications, and their intricate biochemical and molecular mechanism of action within the plant systems during adverse situations.
Author: U.S. Department of Transportation
Publisher: Simon and Schuster
ISBN: 1626363765
Category : House & Home
Languages : en
Pages : 352
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Book Description
Does the identification number 60 indicate a toxic substance or a flammable solid, in the molten state at an elevated temperature? Does the identification number 1035 indicate ethane or butane? What is the difference between natural gas transmission pipelines and natural gas distribution pipelines? If you came upon an overturned truck on the highway that was leaking, would you be able to identify if it was hazardous and know what steps to take? Questions like these and more are answered in the Emergency Response Guidebook. Learn how to identify symbols for and vehicles carrying toxic, flammable, explosive, radioactive, or otherwise harmful substances and how to respond once an incident involving those substances has been identified. Always be prepared in situations that are unfamiliar and dangerous and know how to rectify them. Keeping this guide around at all times will ensure that, if you were to come upon a transportation situation involving hazardous substances or dangerous goods, you will be able to help keep others and yourself out of danger. With color-coded pages for quick and easy reference, this is the official manual used by first responders in the United States and Canada for transportation incidents involving dangerous goods or hazardous materials.
