Author: Franz Joel Leong
Publisher: CRC Press
ISBN: 1439835306
Category : Medical
Languages : en
Pages : 230
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis
A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis
Author: Franz Joel Leong
Publisher: CRC Press
ISBN: 1439835306
Category : Medical
Languages : en
Pages : 230
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis
Publisher: CRC Press
ISBN: 1439835306
Category : Medical
Languages : en
Pages : 230
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis
A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis
Author: Franz Joel Leong
Publisher: CRC Press
ISBN: 1040195709
Category : Medical
Languages : en
Pages : 218
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis
Publisher: CRC Press
ISBN: 1040195709
Category : Medical
Languages : en
Pages : 218
Book Description
An annual death toll of 2 million, coupled with rising drug resistance, highlights the need for the development of new drugs, better diagnostics, and a tuberculosis (TB) vaccine. Addressing these key issues, A Color Atlas of Comparative Pathology of Pulmonary Tuberculosis introduces TB histopathology to the non-histopathologists, students, scientis
Animal Emerging and Reemerging Diseases
Author: Qing Pan
Publisher: Frontiers Media SA
ISBN: 2832534074
Category : Science
Languages : en
Pages : 284
Book Description
Publisher: Frontiers Media SA
ISBN: 2832534074
Category : Science
Languages : en
Pages : 284
Book Description
Imaging in Tuberculosis
Author: Rakesh K Gupta
Publisher: Jaypee Brothers Medical Publishers
ISBN: 9388958977
Category : Medical
Languages : en
Pages : 279
Book Description
Key Features ? The book is a compilation of various facets of imaging in tuberculosis with special emphasis on its clinicopathological correlation ? Also covers important aspects of tuberculosis like epidemiology, clinical perspective and management ? Includes designated chapters on extrapulmonary tuberculosis involving the central nervous system, spine, head and neck, lymph nodes, abdomen, urogenital system and bones and joints ? Written by experts well known for their academic inclination and capability ? The book is a valuable resource for pulmonologists, physicians and postgraduate students.
Publisher: Jaypee Brothers Medical Publishers
ISBN: 9388958977
Category : Medical
Languages : en
Pages : 279
Book Description
Key Features ? The book is a compilation of various facets of imaging in tuberculosis with special emphasis on its clinicopathological correlation ? Also covers important aspects of tuberculosis like epidemiology, clinical perspective and management ? Includes designated chapters on extrapulmonary tuberculosis involving the central nervous system, spine, head and neck, lymph nodes, abdomen, urogenital system and bones and joints ? Written by experts well known for their academic inclination and capability ? The book is a valuable resource for pulmonologists, physicians and postgraduate students.
Advances in Host-Directed Therapies Against Tuberculosis
Author: Petros C. Karakousis
Publisher: Springer Nature
ISBN: 3030569055
Category : Medical
Languages : en
Pages : 325
Book Description
This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective – thus calling for pathway/factor enhancing drugs – or maladaptive – thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
Publisher: Springer Nature
ISBN: 3030569055
Category : Medical
Languages : en
Pages : 325
Book Description
This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective – thus calling for pathway/factor enhancing drugs – or maladaptive – thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.
Imaging of Tuberculosis
Author: Mohamed Fethi Ladeb
Publisher: Springer Nature
ISBN: 3031070402
Category : Medical
Languages : en
Pages : 371
Book Description
This book provides an extensive overview of the role of imaging in the detection, diagnosis, management, and follow-up of tuberculosis. Chapters cover the disease's epidemiology and pathophysiology, microbiological diagnosis and pathology relevant to radiologists, and the distinct aspects of imaging tuberculosis at various locations and body systems. This book discusses recent advances in imaging pertaining to tuberculosis, and addresses the approach to patients with tuberculosis and HIV co-infection. The final chapter offers an algorithmic approach to the diagnosis and management steps of tuberculosis. Imaging of Tuberculosis is an updated and comprehensive reference source that covers imaging of tuberculosis in a structured fashion and is valuable for radiologists.
Publisher: Springer Nature
ISBN: 3031070402
Category : Medical
Languages : en
Pages : 371
Book Description
This book provides an extensive overview of the role of imaging in the detection, diagnosis, management, and follow-up of tuberculosis. Chapters cover the disease's epidemiology and pathophysiology, microbiological diagnosis and pathology relevant to radiologists, and the distinct aspects of imaging tuberculosis at various locations and body systems. This book discusses recent advances in imaging pertaining to tuberculosis, and addresses the approach to patients with tuberculosis and HIV co-infection. The final chapter offers an algorithmic approach to the diagnosis and management steps of tuberculosis. Imaging of Tuberculosis is an updated and comprehensive reference source that covers imaging of tuberculosis in a structured fashion and is valuable for radiologists.
Tuberculosis, Leprosy and Mycobacterial Diseases of Man and Animals
Author: Harshini Mukundan
Publisher: CABI
ISBN: 1780643969
Category : Medical
Languages : en
Pages : 589
Book Description
Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.
Publisher: CABI
ISBN: 1780643969
Category : Medical
Languages : en
Pages : 589
Book Description
Mycobacteria are bacterial pathogens which cause diseases in humans and non-human animals. This monograph will primarily cover the most important and widely researched groups of mycobacteria: members of the Mycobacterium tuberculosis complex (MTC) and Mycobacterium leprae, across a wide range of host species. M. tuberculosis and M. bovis are particularly relevant with the increasing drug resistance and co-infection with HIV associated with M. tuberculosis and the possible cross-infection of badgers and cattle associated with M. bovis. This book will provide a reference for researchers working in different fields creating a work which draws together information on different pathogens, and by considering the diseases in a zoonotic context provides a One Health approach to these important groups of diseases.
Mycobacteria and the Macrophage
Author: Suzie Hingley-Wilson
Publisher: Frontiers Media SA
ISBN: 2832519164
Category : Medical
Languages : en
Pages : 297
Book Description
The macrophage (or “big eater”) is often considered the first cell type to encounter the causative agent of Tuberculosis (TB), Mycobacterium tuberculosis, upon entry to the lung. Once inside the macrophage the tubercle bacillus can survive and even replicate where many other invading pathogens perish. Recent research suggests the bacilli adapts within this hostile environment, treating the macrophage like a Trojan horse. Indeed, cutting-edge techniques have revealed that the degree of bacterial heterogeneity and resistance to antibiotics changes within the macrophage. M. tuberculosis spends most of its life cycle within the macrophage and has adopted specific mechanisms to survive, egress and to recruit more of this niche cell (eg the Type VII secretion system ESX-1). Understanding the host-pathogen interaction in tuberculous infection is key to understanding TB, which remains the number one cause of death from a bacterial infection. In this research topic we aim to cover advances in understanding how the tubercle bacillus adapts and survives within the host cell. Determining the responsible mechanisms may reveal novel ways to target this deadly pathogen and halt its adaptation and transformation within these potentially destructive or permissive cells.
Publisher: Frontiers Media SA
ISBN: 2832519164
Category : Medical
Languages : en
Pages : 297
Book Description
The macrophage (or “big eater”) is often considered the first cell type to encounter the causative agent of Tuberculosis (TB), Mycobacterium tuberculosis, upon entry to the lung. Once inside the macrophage the tubercle bacillus can survive and even replicate where many other invading pathogens perish. Recent research suggests the bacilli adapts within this hostile environment, treating the macrophage like a Trojan horse. Indeed, cutting-edge techniques have revealed that the degree of bacterial heterogeneity and resistance to antibiotics changes within the macrophage. M. tuberculosis spends most of its life cycle within the macrophage and has adopted specific mechanisms to survive, egress and to recruit more of this niche cell (eg the Type VII secretion system ESX-1). Understanding the host-pathogen interaction in tuberculous infection is key to understanding TB, which remains the number one cause of death from a bacterial infection. In this research topic we aim to cover advances in understanding how the tubercle bacillus adapts and survives within the host cell. Determining the responsible mechanisms may reveal novel ways to target this deadly pathogen and halt its adaptation and transformation within these potentially destructive or permissive cells.
Complex Systems and Computational Biology Approaches to Acute Inflammation
Author: Yoram Vodovotz
Publisher: Springer Nature
ISBN: 3030565106
Category : Medical
Languages : en
Pages : 307
Book Description
This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.
Publisher: Springer Nature
ISBN: 3030565106
Category : Medical
Languages : en
Pages : 307
Book Description
This second edition expands upon and updates the vital research covered in its predecessor, by presenting state-of-the-art multidisciplinary and systems-oriented approaches to complex diseases arising from and driven by the acute inflammatory response. The chapters in this volume provide an introduction to different types of computational modeling, and how these methods can be applied to specific inflammatory diseases, with a focus on providing readers a roadmap for integrating advanced mathematical and computational techniques with traditional experimental methods. In this second edition, we cover both well-established and emerging modeling methods, especially state-of-the-art machine learning approaches and the integration of data-driven and mechanistic modeling. This volume introduces the concept of Model-based Precision Medicine as an alternative approach to the current view of Precision Medicine, based on leveraging mechanistic computational modeling to decrease cost while increasing the information value of the data being obtained. By presenting the role of computational modeling as an integrated component of the research process, Complex Systems and Computational Biology Approaches to Acute Inflammation: A Framework for Model-based Precision Medicine offers a window into the recent past, the present, and the future of computationally-augmented biomedical research.
Infectious Diseases and Pathology of Reptiles
Author: Elliott R. Jacobson
Publisher: CRC Press
ISBN: 1420004034
Category : Medical
Languages : en
Pages : 732
Book Description
Far from the line drawings and black-and-white photos of the past, Infectious Diseases and Pathology of Reptiles features high-quality, color photos of normal anatomy and histology, as well as gross, light, and electron microscopic images of pathogens and diseases. Many of these images have never before been published, and come directly from
Publisher: CRC Press
ISBN: 1420004034
Category : Medical
Languages : en
Pages : 732
Book Description
Far from the line drawings and black-and-white photos of the past, Infectious Diseases and Pathology of Reptiles features high-quality, color photos of normal anatomy and histology, as well as gross, light, and electron microscopic images of pathogens and diseases. Many of these images have never before been published, and come directly from