A Cancer Family Syndrome in Twenty-four Kindreds

A Cancer Family Syndrome in Twenty-four Kindreds PDF Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 8

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Book Description

A Cancer Family Syndrome in Twenty-four Kindreds

A Cancer Family Syndrome in Twenty-four Kindreds PDF Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 8

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Book Description


Multiple Primary Cancers

Multiple Primary Cancers PDF Author: Alfred I. Neugut
Publisher:
ISBN:
Category : Health & Fitness
Languages : en
Pages : 504

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Book Description
The purpose of this text is to help develop a better understanding of the nature of cancer, to expand prevention strategies, and to improve diagnostic and prognostic skills centred around multiple primary cancers. Clinical studies focusing on the aetiology of multiple primary cancers, statistical data presented in tables, and discussions on various organ sites and the possible occurrence of multiple primary cancers are addressed throughout the text. The first part reviews various methodological and statistical considerations in the study, management and prevention of primary, secondary and multiple primary cancers. An entire chapter contains tables of incidence rates of various multiple primary cancers that prove helpful in subsequent chapters. Part Two discusses predisposing genetic conditions and various forms of environmental factors that are associated with multiple primary cancers. Finally, the last section review selected types of cancers and focuses on possible clinical implications for occurrences of specific multiple primary cancers.

Concise Handbook of Familial Cancer Susceptibility Syndromes

Concise Handbook of Familial Cancer Susceptibility Syndromes PDF Author:
Publisher:
ISBN: 9780199558391
Category : Cancer
Languages : en
Pages : 93

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Book Description


Brain Tumors

Brain Tumors PDF Author: Francis Ali-Osman
Publisher: Springer Science & Business Media
ISBN: 1592598439
Category : Medical
Languages : en
Pages : 392

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Book Description
Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors is quite complex and the resulting tumors are characterized by a high degree of biological and clinical diversity. Thus, despite the advances of the last two decades, prognosis for patients with malignant brain tumors remains abysmal. Significant progress in the diagnosis, treatment and, ultimately, prevention of these tumors will require both the timely h- nessing of the advances in basic and clinical brain tumor research, and a continuing concerted effort at increasing our understanding of brain tumor biology, in particular, the molecular genetic changes and perturbations of cellular pathways involved in brain oncogenesis and which drive the biological and clinical behavior of the tumors. Brain tumor diagnosis and prognosis, which is still largely based on histopathology and other clinical criteria, will, in the future, acquire a significant molecular component, with the incorporation of knowledge of genes that are mutated, over-expressed, deleted, silenced, or functionally altered in the tumors. Treatment strategies for brain tumors, rather than being empirical, will be rationally developed based on an understanding of the cellular and molecular mechanisms and targets that have been activated, suppressed, or otherwise altered.

Principles of Clinical Cancer Genetics

Principles of Clinical Cancer Genetics PDF Author: Daniel C. Chung
Publisher: Springer Science & Business Media
ISBN: 038793846X
Category : Medical
Languages : en
Pages : 234

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Book Description
Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Applied Informatics

Applied Informatics PDF Author: Hector Florez
Publisher: Springer Nature
ISBN: 3031468139
Category : Computers
Languages : en
Pages : 469

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Book Description
This book constitutes the proceedings of the 6th International Conference on Applied Informatics, ICAI 2023, which took place in Guayaquil, Ecuador, in October 2023. The 30 papers presented in this volume were carefully reviewed and selected from 132 submissions. The contributions are divided into the following thematic blocks: Artificial Intelligence; Data Analysis; Decision Systems; Enterprise Information Systems Applications; Geoinformatics; Health Care Information Systems; Interdisciplinary Information Studies; Learning Management Systems; Virtual and Augmented Reality.

Textbook of Medical Oncology

Textbook of Medical Oncology PDF Author: Franco Cavalli
Publisher: CRC Press
ISBN: 0203092899
Category : Medical
Languages : en
Pages : 476

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Book Description
Effective care of the cancer patient increasingly involves systemic treatment, and as the range of available therapeutic agents continues to expand, the medical oncologist must be fully aware of the rationale for choosing specific drugs and combinations. Textbook of Medical Oncology, 4th edition, is written by a highly acclaimed list of internation

Pediatric Psycho-oncology

Pediatric Psycho-oncology PDF Author: Lori Wiener
Publisher: Oxford University Press, USA
ISBN: 0199335117
Category : Medical
Languages : en
Pages : 433

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Book Description
Pediatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of adolescents living with cancer and their families. Chapters cover a wide range of topics including psychological aspects of particular pediatric cancers and their treatments, how to talk to a child and family at critical times during the disease course, genetic testing, individual, family, educational, psychological and psychiatric interventions, and caring for international patients . Each chapter highlights the necessity of embracing an interdisciplinary approach to ensure that each child has the best options for living with cancer and, when cure is not possible, that death occurs with as much dignity as possible for the child and family. An extensive resource section is appended to provide information on written, online, video, community, national and international services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating pediatric cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Pediatric Psycho-Oncology is an ideal resource for helping pediatric oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing pediatric oncology services or adding psychosocial components to existing clinics.

Tumors of the Central Nervous System, Volume 2

Tumors of the Central Nervous System, Volume 2 PDF Author: M.A. Hayat
Publisher: Springer Science & Business Media
ISBN: 9400706189
Category : Medical
Languages : en
Pages : 449

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Book Description
Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.

DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology

DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology PDF Author: Vincent T. DeVita Jr.
Publisher: Lippincott Williams & Wilkins
ISBN: 1469894556
Category : Medical
Languages : en
Pages : 6697

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Book Description
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues