3D Modelling of Mammalian Embryos and Organs

3D Modelling of Mammalian Embryos and Organs PDF Author: Silvia Garagna
Publisher: Frontiers Media SA
ISBN: 2889716074
Category : Science
Languages : en
Pages : 188

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Book Description

3D Modelling of Mammalian Embryos and Organs

3D Modelling of Mammalian Embryos and Organs PDF Author: Silvia Garagna
Publisher: Frontiers Media SA
ISBN: 2889716074
Category : Science
Languages : en
Pages : 188

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Book Description


Examining the State of the Science of Mammalian Embryo Model Systems

Examining the State of the Science of Mammalian Embryo Model Systems PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309676681
Category : Medical
Languages : en
Pages : 155

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Book Description
Because of the recent advances in embryo modeling techniques, and at the request of the Office of Science Policy in the Office of the Director at the National Institutes of Health, the National Academies of Sciences, Engineering, hosted a 1-day public workshop that would explore the state of the science of mammalian embryo model systems. The workshop, which took place on January 17, 2020, featured a combination of presentations, panels, and general discussions, during which panelists and participants offered a broad range of perspectives. Participants considered whether embryo model systems - especially those that use nonhuman primate cells - can be used to predict the function of systems made with human cells. Presentations provided an overview of the current state of the science of in vitro development of human trophoblast. This publication summarizes the presentation and discussion of the workshop.

Cell Polarity in Development and Disease

Cell Polarity in Development and Disease PDF Author: Douglas W Houston
Publisher: Academic Press
ISBN: 0128125918
Category : Science
Languages : en
Pages : 238

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Book Description
Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. - Provides basic science understanding of cell polarity disease and development - Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer - Includes historical context of cell polarity research for potential future breakthroughs

Kaufman's Atlas of Mouse Development Supplement

Kaufman's Atlas of Mouse Development Supplement PDF Author: Richard Baldock
Publisher: Academic Press
ISBN: 0128009136
Category : Science
Languages : en
Pages : 343

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Book Description
Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. - Provides high-resolution images for best visualization of key developmental processes and structures - Offers in-depth anatomy and morphological views of organ systems - Written descriptions convey developmental origins of the organ systems

Culture Media, Solutions, and Systems in Human ART

Culture Media, Solutions, and Systems in Human ART PDF Author: Patrick Quinn
Publisher: Cambridge University Press
ISBN: 1139917358
Category : Medical
Languages : en
Pages : 307

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Book Description
This volume describes culture media and solutions used in human ART; how they have been developed for in vitro human pre-implantation embryo development, the function and importance of the various components in media and solutions and how they interact, and how the systems in which these are used can influence outcomes. Chapters discuss inorganic solutes, energy substrates, amino acids, macromolecules, cytokines, growth factors, buffers, pH, osmolality, and the interaction of these parameters. The role of incubators and other physical factors are reviewed, along with the relevance and prospects of emerging technologies: morphokinetic analysis using time-lapse imaging and dynamic fluid incubation systems. Results of prospective randomized trials are emphasized to ascertain the added value of these techniques for selecting viable embryos. This comprehensive guide will be invaluable for embryologists, physicians and all personnel involved in the fluid products used in human ART seeking to optimize their successful use of these components.

The Dance of Life

The Dance of Life PDF Author: Magdalena Zernicka-Goetz
Publisher: Basic Books
ISBN: 1541699041
Category : Science
Languages : en
Pages : 238

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Book Description
A renowned biologist's cutting-edge and unconventional examination of human reproduction and embryo research Scientists have long struggled to make pregnancy easier, safer, and more successful. In The Dance of Life, developmental and stem-cell biologist Magdalena Zernicka-Goetz takes us to the front lines of efforts to understand the creation of a human life. She has spent two decades unraveling the mysteries of development, as a simple fertilized egg becomes a complex human being of forty trillion cells. Zernicka-Goetz's work is both incredibly practical and astonishingly vast: her groundbreaking experiments with mouse, human, and artificial embryo models give hope to how more women can sustain viable pregnancies. Set at the intersection of science's greatest powers and humanity's greatest concern, The Dance of Life is a revelatory account of the future of fertility -- and life itself.

The Giant Vesicle Book

The Giant Vesicle Book PDF Author: Rumiana Dimova
Publisher: CRC Press
ISBN: 1351648551
Category : Science
Languages : en
Pages : 1168

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Book Description
Giant vesicles are widely used as a model membrane system, both for basic biological systems and for their promising applications in the development of smart materials and cell mimetics, as well as in driving new technologies in synthetic biology and for the cosmetics and pharmaceutical industry. The reader is guided to use giant vesicles, from the formation of simple membrane platforms to advanced membrane and cell system models. It also includes fundamentals for understanding lipid or polymer membrane structure, properties and behavior. Every chapter includes ideas for further applications and discussions on the implications of the observed phenomena towards understanding membrane-related processes. The Giant Vesicle Book is meant to be a road companion, a trusted guide for those making their first steps in this field as well as a source of information required by experts. Key Features • A complete summary of the field, covering fundamental concepts, practical methods, core theory, and the most promising applications • A start-up package of theoretical and experimental information for newcomers in the field • Extensive protocols for establishing the required preparations and assays • Tips and instructions for carefully performing and interpreting measurements with giant vesicles or for observing them, including pitfalls • Approaches developed for investigating giant vesicles as well as brief overviews of previous studies implementing the described techniques • Handy tables with data and structures for ready reference

Early Mammalian Development

Early Mammalian Development PDF Author: Matthew H. Kaufman
Publisher: CUP Archive
ISBN: 9780521254496
Category : Nature
Languages : en
Pages : 296

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Book Description


Mechanisms of Cellular Differentiation, Organ Development, and Novel Model Systems

Mechanisms of Cellular Differentiation, Organ Development, and Novel Model Systems PDF Author: Benedetta Artegiani
Publisher: Frontiers Media SA
ISBN: 2832501192
Category : Science
Languages : en
Pages : 383

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Book Description


Branching Morphogenesis

Branching Morphogenesis PDF Author: Jamie Davies
Publisher: Springer Science & Business Media
ISBN: 0387308733
Category : Science
Languages : en
Pages : 255

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Book Description
Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on a variety of branching systems to present a state-of-the-art view of the mechanisms that control branching morphogenesis. Systems considered range from single cells, to blood vessel and drainage duct systems to entire body plans, and approaches range from observation through experiment to detailed biophysical modelling. The result is an integrated overview of branching.